|
rs1042034
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The A allele of rs1042034 and the G allele of rs676210 may thus predispose middle-aged and elderly members of the Chinese Yugur population to HL in combination with other genetic or nutritional factors, and could be used as new genetic markers for HL screening.
|
28902930 |
2017 |
|
rs10455872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Topics enriched for CVD and hyperlipidemia had positive correlations with rs10455872 (P < 0.001), replicating a previous finding.
|
30759150 |
2019 |
|
rs1048943
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hyperlipidemia could modulate the effect of CYP1A1 rs1048943 on the periodontal status of GAgP.
|
31032950 |
2019 |
|
rs10748835
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The current study was to determine if coronary heart disease, hypertension, and hyperlipidemia were associated with low-level arsenic exposure and AS3MT gene single nucleotide polymorphism (SNP) A35991G (rs10748835) in rural Texas.
|
22341486 |
2012 |
|
rs11066280
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three gene variants, rs12229654, rs17249754, and rs11066280, were significantly associated with metabolic disorders such as hyperlipidemia and diabetes (P = 0.00071 to 0.0097, respectively).
|
24142389 |
2014 |
|
rs1137101
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Effects of LEP G2548A and LEPR Q223R Polymorphisms on Serum Lipids and Response to Simvastatin Treatment in Chinese Patients With Primary Hyperlipidemia.
|
26984935 |
2017 |
|
rs11542041
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This explains the significant effect of the apoE gene locus on the variability of plasma lipoprotein concentrations and moreover the implication of apoE alleles in the aetiology of multifactorial forms of hyperlipidaemia e.g. familial type III hyperlipidaemia (apoE2; arg158----cys) and polygenic hypercholesterolaemia (apoE4; cys112----arg).
|
3141688 |
1988 |
|
rs11575937
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Heterozygosity for LMNA R482Q mutation causes FPLD, which is associated with increased risk of hyperlipidemia and hypertension.
|
23313286 |
2013 |
|
rs11615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiplicative interactions among SNP rs11615, alcohol drinking, history of T2DM, and history of hyperlipidemia could increase 5.06-fold risk of CAD (P = 1.59 × 10<sup>-9</sup>).
|
28743890 |
2017 |
|
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MTHFR C677T genetic variant contributes to simvastatin's effects among Chinese subjects with primary hyperlipidemia.
|
23865383 |
2013 |
|
rs121918392
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case of hyperlipidemia with homozygous apolipoprotein E5 (Glu3-->Lys).
|
12069856 |
2002 |
|
rs121964971
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, we characterized monocyte heterogeneity in Tg-hCBS apoE(-/-) Cbs(-/-) mice and another severe HHcy mouse model (Tg-S466L Cbs(-/-)) with a disease-relevant mutation (Tg-S466L) that lacks hyperlipidemia.
|
19858416 |
2009 |
|
rs12229654
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three gene variants, rs12229654, rs17249754, and rs11066280, were significantly associated with metabolic disorders such as hyperlipidemia and diabetes (P = 0.00071 to 0.0097, respectively).
|
24142389 |
2014 |
|
rs1251035592
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SLCO1B1 521T > C and 388A > G variants were found to be relatively common in Chinese patients with essential hyperlipidemia.
|
23263738 |
2013 |
|
rs1256046734
|
|
|
0.010 |
GeneticVariation |
BEFREE |
LEPR Q223R polymorphism, but not LEP G2548A, could modulate the efficacy of simvastatin in Chinese patients with primary hyperlipidemia.
|
26984935 |
2017 |
|
rs1256049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
1082A>G (rs1256049) and 1730A>G (rs4986938) showed no statistical association with hyperlipidemia.
|
19927160 |
2010 |
|
rs13281615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In premenopausal women, two environmental factors (history of breastfeeding, and history of benign breast disease) and four genetic variants (TOX3-rs3803662, ESR1-rs2046210, 8q24-rs13281615, and SLC4A7-rs4973768) were considered to be risk predictors, whereas three environmental factors (body mass index, history of breastfeeding, and hyperlipidemia), serum levels of testosterone and 25-hydroxyvitamin D, and two genetic variants (TOX3-rs3803662 and ESR1-rs2046210) were identified as risk predictors.
|
29029469 |
2017 |
|
rs1341991169
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case of hyperlipidemia with homozygous apolipoprotein E5 (Glu3-->Lys).
|
12069856 |
2002 |
|
rs140808909
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Characterization of apolipoprotein E7 (Glu(244)-->Lys, Glu(245)--->Lys), a mutant apolipoprotein E associated with hyperlipidemia and atherosclerosis.
|
9925654 |
1999 |
|
rs1444332461
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate the distribution of statin therapy correlated gene polymorphism allele CYP2D6*10 (C188T) in Ningxia Hui nationality and to discuss the relationship between the gene polymorphism allele CYP2D6*10 (C188T) and the lipid-lowering efficacy of simvastatin and hyperlipidemia.
|
24156754 |
2014 |
|
rs150599989
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Identification of a novel C5L2 variant (S323I) in a French Canadian family with familial combined hyperlipemia.
|
16627811 |
2006 |
|
rs17249754
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three gene variants, rs12229654, rs17249754, and rs11066280, were significantly associated with metabolic disorders such as hyperlipidemia and diabetes (P = 0.00071 to 0.0097, respectively).
|
24142389 |
2014 |
|
rs174537
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among four SNPs, only rs174537G>T differed in allele frequencies between controls and CAD patients after adjustment for age, BMI, cigarette smoking, alcohol consumption, hypertension, diabetes mellitus, and hyperlipidemia (P=0.017).
|
21040914 |
2011 |
|
rs174547
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The CC variant of rs174547 was significantly associated with hyperlipidemia compared with the TT variant (adjusted odds ratio (OR)=1.71, 95% confidence intervals (CI): 1.16-2.54).
|
22490578 |
2012 |
|
rs1799883
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, no major difference was associated with the beta3AR Trp64Arg or FABP2 Ala54Thr polymorphism in terms of type 2 diabetes or hyperlipidemia in young to older Japanese men.
|
11699048 |
2001 |