Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs498005
rs498005
0.010 GeneticVariation BEFREE <b>Results:</b> C allele of rs498005 was significantly correlated with increased risk of AF (OR = 1.412, 95%CI = 1.012-1.970), and the association still exited after adjustment by age, gender, the status of smoking and drinking, histories of diabetes, hyperlipidaemia and myocardial infarction (adjusted OR = 1.473, 95%CI = 1.043-2.081). 31315459

2019

dbSNP: rs1256049
rs1256049
0.010 GeneticVariation BEFREE 1082A>G (rs1256049) and 1730A>G (rs4986938) showed no statistical association with hyperlipidemia. 19927160

2010

dbSNP: rs4986938
rs4986938
0.010 GeneticVariation BEFREE 1082A>G (rs1256049) and 1730A>G (rs4986938) showed no statistical association with hyperlipidemia. 19927160

2010

dbSNP: rs1048943
rs1048943
0.010 GeneticVariation BEFREE Hyperlipidemia could modulate the effect of CYP1A1 rs1048943 on the periodontal status of GAgP. 31032950

2019

dbSNP: rs200960801
rs200960801
0.010 GeneticVariation BEFREE 1082A>G (rs1256049) and 1730A>G (rs4986938) showed no statistical association with hyperlipidemia. 19927160

2010

dbSNP: rs121918392
rs121918392
0.010 GeneticVariation BEFREE A case of hyperlipidemia with homozygous apolipoprotein E5 (Glu3-->Lys). 12069856

2002

dbSNP: rs1341991169
rs1341991169
LPL
0.010 GeneticVariation BEFREE A case of hyperlipidemia with homozygous apolipoprotein E5 (Glu3-->Lys). 12069856

2002

dbSNP: rs738409
rs738409
0.010 GeneticVariation BEFREE Accordingly, the naringenin-betaine cocrystals showed improved anti-hyperlipidemia effects on the C57 BL/6J PNPLA3 I148M transgenic mouse hyperlipidemia model. 30771018

2019

dbSNP: rs2523608
rs2523608
0.010 GeneticVariation BEFREE After stratification, hyperlipidemia remained a risk factor in women (OR = 4.735, 95% CI: 3.375⁻6.643) and men (OR = 3.640, 95% CI: 2.916⁻4.544) with rs2523608 GG genotype. 30934611

2019

dbSNP: rs174537
rs174537
0.010 GeneticVariation BEFREE Among four SNPs, only rs174537G>T differed in allele frequencies between controls and CAD patients after adjustment for age, BMI, cigarette smoking, alcohol consumption, hypertension, diabetes mellitus, and hyperlipidemia (P=0.017). 21040914

2011

dbSNP: rs679899
rs679899
0.010 GeneticVariation BEFREE APOB polymorphisms were identified using mass spectrometry, and five single nucleotide polymorphisms (rs1042034, rs2163204, rs512535, rs676210, and rs679899) and serum lipids were further analyzed. rs1042034 and rs676210 were significantly associated with HL (P<0.05). 28902930

2017

dbSNP: rs2241883
rs2241883
0.010 GeneticVariation BEFREE Association of L-FABP T94A and MTP I128T polymorphisms with hyperlipidemia in Chinese subjects. 25663234

2015

dbSNP: rs3816873
rs3816873
0.010 GeneticVariation BEFREE Association of L-FABP T94A and MTP I128T polymorphisms with hyperlipidemia in Chinese subjects. 25663234

2015

dbSNP: rs694539
rs694539
0.010 GeneticVariation BEFREE At present, more than 200 <i>NNMT</i> single nucleotide polymorphisms (SNPs) have been identified in the databases of the human genome projects; however, the association between rs694539 variation and hyperlipidemia has not been reported yet, and whether there are any SNPs in <i>NNMT</i> significantly associated with hyperlipidemia is still unclear. 27999813

2016

dbSNP: rs140808909
rs140808909
0.010 GeneticVariation BEFREE Characterization of apolipoprotein E7 (Glu(244)-->Lys, Glu(245)--->Lys), a mutant apolipoprotein E associated with hyperlipidemia and atherosclerosis. 9925654

1999

dbSNP: rs879254840
rs879254840
0.010 GeneticVariation BEFREE Characterization of apolipoprotein E7 (Glu(244)-->Lys, Glu(245)--->Lys), a mutant apolipoprotein E associated with hyperlipidemia and atherosclerosis. 9925654

1999

dbSNP: rs573658040
rs573658040
0.010 GeneticVariation BEFREE Digestion with BbvI or Fnu4HI allows for rapid restriction isotyping for the rare apolipoprotein E R145C mutation associated with hyperlipidemia. 7735921

1995

dbSNP: rs769455
rs769455
0.010 GeneticVariation BEFREE Digestion with BbvI or Fnu4HI allows for rapid restriction isotyping for the rare apolipoprotein E R145C mutation associated with hyperlipidemia. 7735921

1995

dbSNP: rs1137101
rs1137101
0.010 GeneticVariation BEFREE Effects of LEP G2548A and LEPR Q223R Polymorphisms on Serum Lipids and Response to Simvastatin Treatment in Chinese Patients With Primary Hyperlipidemia. 26984935

2017

dbSNP: rs6214
rs6214
0.010 GeneticVariation BEFREE Elders with GG genotype of rs6214 and AC or CC genotypes of rs2854744 had a 3.18-fold (95% CI 1.02-9.89) risk of having low ASMI compared with those with the AA and AA genotype, after adjusting for age, gender, smoking, exercise, hyperlipidemia, and albumin level. 25548030

2015

dbSNP: rs2854744
rs2854744
0.010 GeneticVariation BEFREE Elders with GG genotype of rs6214 and AC or CC genotypes of rs2854744 had a 3.18-fold (95% CI 1.02-9.89) risk of having low ASMI compared with those with the AA and AA genotype, after adjusting for age, gender, smoking, exercise, hyperlipidemia, and albumin level. 25548030

2015

dbSNP: rs662799
rs662799
0.010 GeneticVariation BEFREE Excess risk for low HDL-C and hyperlipidemia was associated with rs662799 genotype alleles of APOA5 SNPs in older Chinese adults. 29758349

2018

dbSNP: rs717620
rs717620
0.010 GeneticVariation BEFREE Female Chinese patients with hyperlipidemia carrying rs717620 GA/AA genotypes might have reduced benefit from simvastatin treatment. 30024814

2018

dbSNP: rs1805087
rs1805087
MTR
0.010 GeneticVariation BEFREE Further study is needed to confirm the role of HHcy and MS A2756G mutation in the development of hyperlipidemia. 19263808

2008

dbSNP: rs2228314
rs2228314
0.010 GeneticVariation BEFREE Further work is necessary to confirm the role of 1784G>C in the development of hyperlipidemia. 15547298

2005