Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), nucleotide excision repair (XPC-PAT, XPA-23G>A, ERCC1-19007T>C and XPD-L751Q), recombination (XRCC3-T241M) and alkylation damage reversal (MGMT-L84F) were tested for their potential role in the development of GC by using logistic regression models. 20817763

2010

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE To investigate the association between Ser326Cys human oxoguanine glycosylase 1 (hOGG1) polymorphism and atrophic gastritis and gastric cancer after Helicobacter pylori (H. pylori) eradication. 20845517

2010

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE This variant decreased the gene promoter activity by approximately 17.8% (P = 0.041) and exhibited a synergistic effect with the missense mutation p.Ser326Cys of hOGG1 by enhancing susceptibility to gastric cancers. 21822670

2011

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE The significant effects of hOGG1 Ser326Cys polymorphism on colorectal, breast, bladder, prostate, esophageal, and gastric cancer were not detected. 22114677

2011

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE Our result could explain the association between hOGG1 Ser326Cys polymorphism and GC risk. 22294108

2012

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE This meta-analysis provided evidence that hOGG1 S326C genetic polymorphism was not associated with increased risk of gastric cancer. 22296498

2012

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE Taken together, the results suggest that the hOGG1 Ser326Cys polymorphism may contribute to susceptibility to gastric cancer. 22343785

2012

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE No significant association was found for either allele or genotype with gastric cancer (odds ratio [OR]=0.96; 95% confidence interval [95% CI]: 0.82-1.13; P=0.66), and this was also the case after combining 326Ser/Cys and 326Ser/Ser genotypes together (OR=0.87; 95% CI: 0.63-1.20; P=0.40), or 326Cys/Cys and 326Ser/Cys together (OR=1.03; 95% CI: 0.87-1.22; P=0.72). 22471492

2011

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE To clarify any association between the hOGG1 Ser326Cys polymorphism and susceptibility to gastric cancer. 22799296

2012

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE Lack of association between the hOGG1 gene Ser326Cys polymorphism and gastric cancer risk: evidence from a case-control study and a meta-analysis. 26600527

2015

dbSNP: rs1052133
rs1052133
0.100 GeneticVariation BEFREE This meta-analysis showed there was no association between hOGG1 rs1052133 and GC. 28415729

2017

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE To evaluate the association between genetic polymorphism of miR-196a-2 (rs11614913) and risk of gastric cancer, a hospital-based case-control study was conducted in a Chinese population. 19834808

2010

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE We evaluated the associations of three SNPs (rs11614913, rs2910164, and rs3746444) in pre-miRNAs (miR-196a2, miR-146a, and miR-499) with the risk of gastric cancer (GC) and peptic ulcer diseases, and with the severity of Helicobacter pylori-induced gastritis in Japanese population. 21073609

2010

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE We analyzed the correlations of rs11614913 polymorphism with gastric cancer susceptibility in test and validation sets. 23423813

2013

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE The rs2910164/rs2292832/rs11614913 CTT and CCT haplotypes seems to have a protective role against GC (p = 0.002 and p = 0.001, respectively). 24379078

2014

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE We found that rs11614913 and rs2910164 do not pose general cancer risk, but rs11614913 may influence gastric cancer in Japanese elderly population. 24716941

2014

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE The rs11614913 (T>C), rs2910164 (C>T), and rs3746444 (A>G) SNPs were genotyped in 130 advanced GCs performing chemotherapy. 25202115

2014

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE There is no significant association between rs2910164 and rs11614913 and the risk of human gastric cancer. 26215064

2015

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE In summary, the results suggested that the miR-146a rs2910164 polymorphism was related to gastric cancer risk in Asians but not in Caucasians, and no distinct correlation seemed to exist between the miR-196a-2 rs11614913 polymorphism and the risk of gastric cancer. 26345790

2015

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE Our studies suggested that the miR-146a rs2910164 polymorphism might marginally contribute to a decreased risk of gastric cancer, especially in Caucasians, whereas the miR-196a2 rs11614913 polymorphism might not be associated with susceptibility to GC. 26406571

2015

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE By logistic regression analysis, we found that the CC genotype of rs11614913 was associated with an increased risk of gastric cancer in a codominant model (OR = 2.68, 95%CI = 1.17-6.44). 27173281

2016

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE The results demonstrated that miR-196a2 rs11614913 was significantly associated with a decreased cancer risk, in particular with a decreased risk for colorectal cancer and gastric cancer, or for Asian population subgroup. 29371991

2017

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE To investigate the possible relations between the TS 3'-UTR and MTHFR C677T polymorphisms and environmental factors impacting on risk of esophageal and stomach cancers, we conducted a case-control study in a high incidence region of China for these cancers. 15244514

2004

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE C677T, A1298C and G1793A) and their haplotypes are associated with the risk of gastric cancer. 15643524

2005

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE We performed a case-control study to examine the relationship between MTHFR C677T gene polymorphism (MTHFR677C/T) and gastric cancer susceptibility in at-risk populations in central Italy. 16094648

2006