|
rs1800497
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To examine the potential moderating role of DRD2 polymorphism (rs1800497) in the association between stressful life events and depressive symptoms among young adults.
|
17585060 |
2007 |
|
rs4680
|
|
|
0.060 |
GeneticVariation |
BEFREE |
To examine the impact of the catechol-O-methyltransferase (COMT) val(158)met allele on depressive symptoms in young children exposed to early severe social deprivation as a result of being raised in institutions.
|
20403637 |
2010 |
|
rs7973260
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To examine the associations between genetic variants of KSR2 (kinase suppressor of RAS)-rs7973260, RAPGEF6 (guanine nucleotide exchange factor 6)-rs3756290, LOC105377703-rs4481363, and subjective well-being (SWB) and depressive symptoms (DSs) in Chinese elders, which were recently associated in a genome-wide association study conducted in Caucasians.
|
28537769 |
2017 |
|
rs6295
|
|
|
0.030 |
GeneticVariation |
BEFREE |
To determine whether post-injury depressive symptoms, and pre-injury major life stressors and genetic factors (HTR1A C(-1019)G alleles; rs6295) are more common in children with mild traumatic brain injury (mTBI) who develop postconcussion syndrome (PCS) symptoms compared with children with asymptomatic mTBI.
|
23992222 |
2014 |
|
rs1876831
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization.
|
24075295 |
2014 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Thus, we assessed whether the functional single nucleotide polymorphism (SNP) on the BDNF gene, Val66Met, moderated the relationship between depressive symptoms and perceived social support and unsupportive relationships, and whether these associations differed by gender.
|
31364951 |
2020 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Thus, we assessed whether the functional single nucleotide polymorphism (SNP) on the BDNF gene, Val66Met, moderated the relationship between depressive symptoms and perceived social support and unsupportive relationships, and whether these associations differed by gender.
|
31364951 |
2020 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study suggests that C3435T polymorphisms in the ABCB1 gene are strongly associated with a predisposition to depression development, the severity of depressive symptoms and the effectiveness of therapy with using different groups of antidepressant agents.
|
26664259 |
2015 |
|
rs6313
|
|
|
0.040 |
GeneticVariation |
BEFREE |
This study suggests a mechanism for the generation of different neuropsychiatric symptoms in AD from a single nucleotide polymorphism with reduced receptor binding in T102C 5-HT2A receptor gene homozygotes correlating with susceptibility to depressive symptoms, whereas the relative preservation of receptor binding in heterozygotes with AD correlating with susceptibility to hallucinations.
|
17481814 |
2007 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study represents the first replication of the BDNF Val66Met ⁎ 5-HTTLPR ⁎ childhood maltreatment effect on self-reported depression symptoms using a rigorous maltreatment interview.
|
26070769 |
2015 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study represents the first replication of the BDNF Val66Met ⁎ 5-HTTLPR ⁎ childhood maltreatment effect on self-reported depression symptoms using a rigorous maltreatment interview.
|
26070769 |
2015 |
|
rs53576
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study examined the main and interaction effects of the <i>OXTR</i> rs53576 genotype in distinguishing four subgroups identified by symptom profiles of PTSD and depression symptoms using latent profile analysis.<b>Design:</b> A cross-sectional design with a gene-environment interaction approach was adopted in the current study.<b>Methods:</b> This study was a secondary data analysis conducted on a sample of 1196 adult earthquake survivors.
|
31771350 |
2020 |
|
rs9470080
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These SNPs were also associated with an increased risk of depressive symptoms (rs9470080: OR 1.19 (95%CI 1.0; 1.4)).
|
21316860 |
2011 |
|
rs1800795
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Therefore, we examined in a Hungarian population sample of 1053 volunteers with European origins if rs1800795 polymorphism can affect depression symptoms measured by Zung Self-rating Depression Scale (ZSDS), and Brief Symptom Inventory (BSI).
|
26821321 |
2016 |
|
rs11046205
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was also a significant association between a different ABCC9 gene variant (rs11046205) and depressive symptoms.
|
23780892 |
2013 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There was a significant interaction between C-reactive protein (CRP) and the BDNF Val66met polymorphism in predicting cognitive depressive symptoms (p=.004), such that higher CRP was related to more cognitive depressive symptoms among Met allele carriers, but not among Val/Val homozygotes.
|
26967918 |
2016 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There was a significant interaction between C-reactive protein (CRP) and the BDNF Val66met polymorphism in predicting cognitive depressive symptoms (p=.004), such that higher CRP was related to more cognitive depressive symptoms among Met allele carriers, but not among Val/Val homozygotes.
|
26967918 |
2016 |
|
rs6313
|
|
|
0.040 |
GeneticVariation |
BEFREE |
There was a significant gene-environment interaction, such that the urban residency was associated with low depressive symptoms in individuals carrying the T/T or T/C genotype of the T102C polymorphism, but not in those carrying the C/C genotype.
|
17510953 |
2007 |
|
rs4290270
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The tryptophan hydroxylase-2 gene polymorphism rs4290270 may not be a susceptibility locus for primary insomnia in Han Chinese, but it may be a marker of depressive symptoms.
|
29952309 |
2018 |
|
rs17466684
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNP of <i>EPHX2</i> (rs17466684) gene polymorphism is associated with depression symptoms among Malaysian women with GDM.
|
31801286 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The serotonin transporter polymorphism (5-HTTLPR) and the brain-derived neurotrophic factor (BDNF) val66met polymorphism have both been linked to depression symptoms and to depression diagnosis (MDD) in interaction with adversity; there have also been failures to find the effects.
|
21420735 |
2011 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The serotonin transporter polymorphism (5-HTTLPR) and the brain-derived neurotrophic factor (BDNF) val66met polymorphism have both been linked to depression symptoms and to depression diagnosis (MDD) in interaction with adversity; there have also been failures to find the effects.
|
21420735 |
2011 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Role of the Val66Met Polymorphism of the Brain Derived Neurotrophic Factor Gene in Coping Strategies Relevant to Depressive Symptoms.
|
23824678 |
2013 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Role of the Val66Met Polymorphism of the Brain Derived Neurotrophic Factor Gene in Coping Strategies Relevant to Depressive Symptoms.
|
23824678 |
2013 |
|
rs2227631
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The purpose of this study was to explore the association between the SERPINE1 promoter polymorphisms (rs1799889 and rs2227631) and the risk of depression in AD and to determine the relationship between these 2 polymorphisms and the response to paroxetine treatment in AD patients with depressive symptoms.
|
22503724 |
2012 |