Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs738409
rs738409
PNPLA3
0.800 GeneticVariation BEFREE Numerous studies in humans link a nonsynonymous genetic polymorphism (I148M) in adiponutrin (ADPN) to various forms of fatty liver disease and liver cirrhosis. 22560221

2012
dbSNP: rs738409
rs738409
PNPLA3
0.800 GeneticVariation BEFREE In addition, there were marked differences in rs738409 genotype distributions between type4 subgroup corresponding to NASH and the other three subgroups (p = 4.8 × 10(-6), OR = 1.96, 95%CI: 1.47-2.62). 22719876

2012
dbSNP: rs738409
rs738409
PNPLA3
0.800 GeneticVariation BEFREE The adiponutrin/PNPLA3 (patatin-like phospholipase domain-containing protein 3) variant I148M has recently emerged as an important marker of human fatty liver disease. 21145868

2011
dbSNP: rs738409
rs738409
PNPLA3
0.800 GeneticVariation BEFREE Interestingly, the rs738</span>409 G allele was strongly associated with the severity of steatosis (P < 0.0001), the presence of NASH (P < 0.0001), hepatocellular ballooning (P < 0.0001), lobular inflammation (P < 0.0001), and the presence of fibrosis (P = 0.01) independently of confounders. 20648474

2010
dbSNP: rs738491
rs738491
SAMM50 ; PNPLA3
0.710 GeneticVariation BEFREE The rs12743824 and rs738491 SNPs were independently associated with FLD and steatohepatitis, respectively. 26352879

2015
dbSNP: rs2896019
rs2896019
PNPLA3
0.710 GeneticVariation BEFREE In this study, we report the association of the rs738407, rs738409, and rs2896019 variants of the patatin-like phospholipase domain-containing protein 3 (PNPLA3) (adiponutrin) gene with nonalcoholic steatohepatitis (NASH) (χ(2)=14.528, p=0.001; χ(2)=18.882, p=0.000; χ(2)=7.449, p=0.024, respectively) in 80 patients with NASH and 303 healthy controls. 24831885

2014
dbSNP: rs2896019
rs2896019
PNPLA3
0.710 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs738491
rs738491
SAMM50 ; PNPLA3
0.710 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs1007863
rs1007863
SAMM50 ; PARVB
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs1010022
rs1010022
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs1010023
rs1010023
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs11090617
rs11090617
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs12483959
rs12483959
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs1461729
rs1461729
LOC157273
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs1474745
rs1474745
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs1883349
rs1883349
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs1883350
rs1883350
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs1977081
rs1977081
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2072905
rs2072905
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2072907
rs2072907
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2073079
rs2073079
SAMM50
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2073080
rs2073080
SAMM50 ; PARVB
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2073081
rs2073081
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2076211
rs2076211
PNPLA3
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2126259
rs2126259
LOC157273
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013