rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We conclude that the TP53 R72P polymorphism may contribute to the etiology of colorectal cancer in the Chinese population, particularly among alcohol consumers.
|
17599946 |
2007 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, heterozygosity and mutant homozygosity as well as the combination of both TP53 Arg72Pro and CDH1 rs16260 polymorphisms are responsible to increase the risk of colorectal cancer development in Bangladeshi population.
|
28554075 |
2017 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We did not identify an association between TP53 rs1042522 and colorectal cancer.
|
20615891 |
2010 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of Arg72Pro of P53 polymorphism with colorectal cancer susceptibility risk in Malaysian population.
|
22393962 |
2011 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
TP53 Arg 72Pro and MDM2 SNP309 polymorphisms and colorectal cancer risk: a west Algerian population study.
|
25537146 |
2015 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between p53 Arg72Pro polymorphism and colorectal cancer risk in Asian population: a meta-analysis.
|
30316510 |
2018 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The p53 R72P genotype was identified by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in 78 consecutive colorectal cancer patients with liver metastases and 214 age- and sex-matched cases with nonmetastatic colorectal cancer.
|
18988302 |
2008 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We have previously reported that the common, functionally different variants Arg72Pro in p53 and Arg462Gln in RNASEL are associated with the age of disease onset of colorectal cancer in Lynch syndrome patients.
|
17224235 |
2007 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of mRNA expression of TP53 and the TP53 codon 72 Arg/Pro gene polymorphism with colorectal cancer risk in Asian population: a bioinformatics analysis and meta-analysis.
|
29872345 |
2018 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
TP53 R72P and MDM2 SNP309 polymorphisms and colorectal cancer risk: the Fukuoka Colorectal Cancer Study.
|
21051533 |
2011 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
TP53 Pro47Ser and Arg72Pro polymorphisms and colorectal cancer predisposition in an ethnic Kashmiri population.
|
20449797 |
2010 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We assessed the association of TP53 Arg72Pro and p53PIN3 polymorphisms with colorectal cancer risk and their possible interaction with nonsteroidal anti-inflammatory drug use.
|
17622940 |
2007 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Among 442 colorectal cancer cases and 904 controls, we observed no significant overall association between p53 Arg72Pro genotype and colorectal cancer (multivariate OR = 1.14, 95% CI = 0.90-1.45).
|
16721787 |
2006 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The association between the TP53 Arg72Pro polymorphism and colorectal cancer: An updated meta-analysis based on 32 studies.
|
27901479 |
2017 |
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Age of diagnosis of colorectal cancer in HNPCC patients is more complex than that predicted by R72P polymorphism in TP53.
|
16353134 |
2006 |
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Polymorphism OGG1 S326C was associated with an increased risk of colorectal cancer [odds ratio (OR), 2.3; 95% confidence interval (95% CI), 1.1-5.0], the risk being higher in younger individuals.
|
16609022 |
2006 |
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Carriers of the variant allele OGG1 Ser326Cys polymorphism had a lowered risk of colorectal cancer, OR=0.56 (95% confidence interval 0.33-0.95), while no association were found with risk of adenomas.
|
15946795 |
2005 |
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of OGG1 Ser326Cys polymorphism with colorectal cancer risk: a meta-analysis.
|
21695387 |
2011 |
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The analysis of binary genotype combinations showed increased co</span>lorectal cancer risk in individuals simultaneously homozygous for the variant alleles of APE1 Asn148Glu and hOGG1 Ser326Cys (OR: 6.37; 95% CI: 1.40-29.02; p=0.02).
|
17991492 |
2008 |
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
DNA repair gene 8-oxoguanine DNA glycosylase Ser326Cys polymorphism and colorectal cancer risk in a Kashmiri population.
|
21899442 |
2012 |
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analysis of all 13 studies showed that OGG1 rs1052133 polymorphism was significantly associated with the risk of colo</span>rectal cancer in Caucasian population (Cys versus Ser OR = 1.20, 95% CI = 1.03-1.39, P = 0.02; CysCys versus SerSer OR = 1.44, 95% CI = 1.04-2.00, P = 0.03; CysCys versus SerSer/SerCys OR = 1.39, 95% CI = 1.15-1.67, P = 0.0005).
|
23975367 |
2014 |
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggest that unlike for other cancer types, the hOGG1 Ser326Cys polymorphism is not a major genetic risk factor for colorectal cancer.
|
17827862 |
2007 |
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The overall data indicated a significant association of hOGG1 Ser326</span>Cys polymorphism on colorectal cancer risk (allele model OR = 1.14, 95 %CI 1.02-1.27; homozygote model OR = 1.32, 95 %CI 0.92-1.92; recessive model OR = 1.12, 95 %CI 1.00-1.26; dominant model OR = 1.15, 95 %CI 1.00-1.32).
|
25227662 |
2014 |
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that there is no robust association between hOGG1 Ser326Cys polymorphism and colorectal cancer.
|
22526153 |
2012 |
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
GPX1 Pro(198)Leu, hOGG1 Ser(326)Cys and erythrocyte GPX enzyme activity were not associated with risk of colorectal cancer.
|
19428376 |
2009 |