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rs118049207
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification and interaction analyses showed that SND1 rs118049207</span> multiplicatively interacted with the sex and drinking status of the patients to enhance their colorectal cancer risk (P = 1.56×10-3 and 1.41×10-2, respectively).
|
31579913 |
2020 |
|
rs1267969615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest that the angiotensin-converting enzyme I/D and angiotensinogen M235T polymorphisms are unlikely to correlate with colorectal cancer.
|
31642377 |
2020 |
|
rs2070804
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We demonstrated the association of HSPB1 genetic polymorphisms rs2070804 with tumor depth with colorectal cancer.
|
31364192 |
2020 |
|
rs2279744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphism T309G (rs2279744) in the MDM2 gene was studied in patients with colorectal cancer (n=135) and healthy control subjects (n=145) using the polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method.
|
31424672 |
2020 |
|
rs2470151
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings suggest that <i>RP11-108K3.2</i> rs2470151 had a significant association with the risk of colorectal cancer; this may help to predict the susceptibility of colorectal cancer in Chinese populations.
|
31789575 |
2020 |
|
rs2555639
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphism rs2555639 in 15-PGDH and colorectal cancer metastasis.
|
31646799 |
2020 |
|
rs699
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest that the angiotensin-converting enzyme I/D and angiotensinogen M235T polymorphisms are unlikely to correlate with colorectal cancer.
|
31642377 |
2020 |
|
rs1057519860
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Growth suppression of colorectal cancer expressing S492R EGFR by monoclonal antibody CH12.
|
30671888 |
2019 |
|
rs1063169
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs7101 and rs1063169 polymorphisms in the noncoding region of FOS are associated with the risk of developing colorectal cancer and the progression of colorectal cancer, which may be because the mutation enhances the expression of c-Fos protein to promote the incidence and development of colorectal cancer.
|
31261535 |
2019 |
|
rs1064795841
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between KRAS G13D mutations and anastomotic recurrence in colorectal cancer: Two case reports.
|
30896620 |
2019 |
|
rs10889677
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphism rs10889677 in miRNAs Let-7e and Let-7f binding site of IL23R gene is a strong colorectal cancer determinant: Report and meta-analysis.
|
31546198 |
2019 |
|
rs1282801317
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, two novel non-hotspot <i>KRAS</i> mutations were functionally characterized <i>in vitro</i>: KRAS E31D was identified from a genetic screen of colorectal cancer specimens at the UP-National Institutes of Health.
|
31289513 |
2019 |
|
rs13072632
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied thirteen single nucleotide polymorphisms (SNPs) located in SFRP3 (rs7775), CTNNB1 (β-catenin) [rs4135385, rs13072632], APC (rs454886, rs459552), LRP6 (rs2075241, rs2284396), DKK4 (rs3763511), DKK3 (rs6485350), TCF4 (rs12255372) and AXIN2 (rs3923086, rs3923087, rs4791171) in patients with colorectal cancer (n = 122) and controls (n = 110).
|
31485167 |
2019 |
|
rs1428
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overall analysis found that rs7336610 and rs1428 and haplotype CTAGA were significantly associated with increased risk of colorectal cancer.
|
30941921 |
2019 |
|
rs1456315
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genotyping analysis for SNP rs1456315 showed increased association with colorectal cancer with the homozygous CC variant allele (OR: 2.09; χ2 = 4.95; CI: 1.08-4.02; p = 0.02), the minor allele frequency, and additive genotype, respectively (OR: 1.55; χ2 = 6.24; CI: 1.09-2.19; p = 0.01) & (OR: 1.64; χ2 = 4.04; CI: 1.01-2.67; p = 0.04).
|
31487296 |
2019 |
|
rs146639652
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Germline mutation p.N363K in POLE is associated with an increased risk of colorectal cancer and giant cell glioblastoma.
|
30368636 |
2019 |
|
rs1590
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on these findings, the rs1590 variant in the 3'-UTR of TGFBR1 may contribute to the susceptibility to colorectal cancer, predominantly by altering miR-532-5p binding.
|
29971498 |
2019 |
|
rs16917496
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs16917496 polymorphism including CC, CT and TT genotypes was analyzed in patients with colorectal cancer; the CC genotype was identified to be independently associated with longer post-operative survival times using multivariate analysis (relative risk, 2.406; 95% confidence interval, 1.017-5.691; P=0.046).
|
30881512 |
2019 |
|
rs17026425
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed suggestive evidence (<i>P</i> < 0.05) for eight variants (rs17026425, rs17057166, rs6854845, rs1728400, rs17693104, rs202280, rs6797464, and rs823920) in all colorectal cancer and two variants (rs17026425 and rs6854845) in rectal cancer that were concordant with previous reports.
|
31488414 |
2019 |
|
rs1725459
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In overall and subgroup (defined via body mass index, exercise, and dietary-fat intake) analyses, we identified 2 SNPs (<i>LINC00460</i> rs1725459 and <i>MTRR</i> rs722025) and lifetime cumulative exposure to estrogen (oral contraceptive use) and cigarette smoking as the most common and strongest predictive markers for colorectal cancer risk across the analyses.
|
31554631 |
2019 |
|
rs17735387
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Gender stratification analysis found that rs7336610, rs7318578, rs17735387, and rs1428 were significantly associated with colorectal cancer risk in males.
|
30941921 |
2019 |
|
rs2075241
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied thirteen single nucleotide polymorphisms (SNPs) located in SFRP3 (rs7775), CTNNB1 (β-catenin) [rs4135385, rs13072632], APC (rs454886, rs459552), LRP6 (rs2075241, rs2284396), DKK4 (rs3763511), DKK3 (rs6485350), TCF4 (rs12255372) and AXIN2 (rs3923086, rs3923087, rs4791171) in patients with colorectal cancer (n = 122) and controls (n = 110).
|
31485167 |
2019 |
|
rs2281611
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic associations between the miRNA polymorphisms miR-130b (rs373001), miR-200b (rs7549819), and miR-495 (rs2281611) and colorectal cancer susceptibility.
|
31117970 |
2019 |
|
rs2284396
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied thirteen single nucleotide polymorphisms (SNPs) located in SFRP3 (rs7775), CTNNB1 (β-catenin) [rs4135385, rs13072632], APC (rs454886, rs459552), LRP6 (rs2075241, rs2284396), DKK4 (rs3763511), DKK3 (rs6485350), TCF4 (rs12255372) and AXIN2 (rs3923086, rs3923087, rs4791171) in patients with colorectal cancer (n = 122) and controls (n = 110).
|
31485167 |
2019 |
|
rs2632159
|
|
|
0.010 |
GeneticVariation |
BEFREE |
lncRNA-<i>PCAT1</i> rs2632159 polymorphism could be a biomarker for colorectal cancer susceptibility.
|
31253700 |
2019 |