INSR, insulin receptor, 3643

N. diseases: 338; N. variants: 71
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability 		group Behavior and Behavior Mechanisms; Mental Disorders; Nervous System Diseases; Pathological Conditions, Signs and Symptoms Mental or Behavioral Dysfunction 2502 53 0.300 strong 0
CUI: C0020459
Disease: Hyperinsulinism
Hyperinsulinism 		disease Nutritional and Metabolic Diseases Disease or Syndrome 376 33 0.700 limited 0.870 25 1989 2016
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease Endocrine System Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 1671 1522 0.700 0.932 95 5 1985 2016
CUI: C0265344
Disease: Donohue Syndrome
Donohue Syndrome 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases; Musculoskeletal Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 9 16 0.800 0.961 64 16 1985 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		group Endocrine System Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 1506 440 0.200 0.854 41 1 1989 2016
CUI: C0028754
Disease: Obesity
Obesity 		disease Nutritional and Metabolic Diseases; Pathological Conditions, Signs and Symptoms Disease or Syndrome 1960 811 0.100 0.929 28 4 1987 2016
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome 		disease Endocrine System Diseases; Female Urogenital Diseases and Pregnancy Complications; Neoplasms Disease or Syndrome 525 181 0.200 0.963 28 13 1991 2016
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		disease Neoplasms; Skin and Connective Tissue Diseases Neoplastic Process 5053 1365 0.100 1.000 27 1990 2018
CUI: C0011847
Disease: Diabetes
Diabetes 		disease Disease or Syndrome 1267 349 0.100 0.852 27 1989 2016
CUI: C0271695
Disease: Rabson-Mendenhall Syndrome
Rabson-Mendenhall Syndrome 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases; Musculoskeletal Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 3 10 0.800 1.000 27 10 1986 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		disease Neoplasms; Skin and Connective Tissue Diseases Neoplastic Process 4962 1839 0.100 1.000 27 1990 2018
CUI: C0271689
Disease: Insulin Receptor, Defect in
Insulin Receptor, Defect in 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases; Musculoskeletal Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 1 11 0.310 1.000 21 11 1988 2017
CUI: C0342278
Disease: Diabetes Mellitus, Insulin-Resistant, with Acanthosis Nigricans
Diabetes Mellitus, Insulin-Resistant, with Acanthosis Nigricans 		disease Endocrine System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases Disease or Syndrome 1 11 0.600 20 11 1988 2017
CUI: C0271690
Disease: Type 2 diabetes mellitus with acanthosis nigricans
Type 2 diabetes mellitus with acanthosis nigricans 		disease Disease or Syndrome 1 10 0.100 19 10 1956 2014
CUI: C0342336
Disease: Insulin resistance - type A
Insulin resistance - type A 		disease Disease or Syndrome 5 0.400 1.000 17 1988 2017
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		disease Nutritional and Metabolic Diseases Disease or Syndrome 487 37 0.500 0.929 15 1984 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		disease Digestive System Diseases; Neoplasms Neoplastic Process 3592 419 0.100 1.000 13 1989 2014
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		disease Mental Disorders; Nervous System Diseases Disease or Syndrome 1981 1062 0.590 1.000 11 2002 2016
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		phenotype Nutritional and Metabolic Diseases Disease or Syndrome 325 55 0.390 1.000 10 1 1991 2016
CUI: C0000889
Disease: Acanthosis Nigricans
Acanthosis Nigricans 		disease Skin and Connective Tissue Diseases Disease or Syndrome 34 8 0.200 0.900 10 1 1989 2014
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		group Digestive System Diseases; Neoplasms Neoplastic Process 1320 7 0.100 1.000 10 1989 2011
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		phenotype Neoplasms; Pathological Conditions, Signs and Symptoms Neoplastic Process 4064 159 0.090 1.000 9 1986 2016
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		disease Male Urogenital Diseases; Neoplasms Neoplastic Process 3238 563 0.090 1.000 9 2008 2016
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		disease Neoplastic Process 3144 756 0.090 1.000 9 2008 2016
CUI: C0027126
Disease: Myotonic Dystrophy
Myotonic Dystrophy 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases Disease or Syndrome 124 4 0.070 1.000 7 1987 2016