Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders
0.310 Biomarker group PSYGENET On the basis of these results, we conclude that GADD45b may be increased in psychosis compensatory to its inability to access gene promoter regions. 22048458 2012
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders
0.310 Biomarker group PSYGENET Gadd45b is abnormally expressed in subjects with autism and psychosis, two disorders associated with cognitive deficits. 22802593 2012
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders
0.310 Biomarker group BEFREE On the basis of these results, we conclude that GADD45b may be increased in psychosis compensatory to its inability to access gene promoter regions. 22048458 2012
CUI: C0349204
Disease: Nonorganic psychosis
Nonorganic psychosis
0.310 Biomarker disease PSYGENET Gadd45b is abnormally expressed in subjects with autism and psychosis, two disorders associated with cognitive deficits. 22802593 2012
CUI: C0349204
Disease: Nonorganic psychosis
Nonorganic psychosis
0.310 Biomarker disease BEFREE On the basis of these results, we conclude that GADD45b may be increased in psychosis compensatory to its inability to access gene promoter regions. 22048458 2012
CUI: C0349204
Disease: Nonorganic psychosis
Nonorganic psychosis
0.310 Biomarker disease PSYGENET On the basis of these results, we conclude that GADD45b may be increased in psychosis compensatory to its inability to access gene promoter regions. 22048458 2012
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders
0.300 Biomarker group CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0274861
Disease: Arsenic Poisoning, Inorganic
Arsenic Poisoning, Inorganic
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
Nervous System, Organic Arsenic Poisoning
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0311375
Disease: Arsenic Poisoning
Arsenic Poisoning
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0751851
Disease: Arsenic Encephalopathy
Arsenic Encephalopathy
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0751852
Disease: Arsenic Induced Polyneuropathy
Arsenic Induced Polyneuropathy
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 AlteredExpression disease BEFREE Subsequently, lncRNA FENDRR and GADD45B were revealed to have poor expressions in HCC. 31351327 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 Biomarker disease BEFREE Thus, these data reveal nuclear receptor CAR interacts with GADD45B to repress p38 MAPK signaling and elicit hepatocyte proliferation in male mice.<b>Implications:</b> This GADD45B-regulated male-predominant proliferation can be expanded as a phenobarbital promotion signal of HCC development in future studies.<b>Visual Overview:</b> http://mcr.aacrjournals.org/content/molcanres/16/8/1309/F1.large.jpg <i></i>. 29716964 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 AlteredExpression disease BEFREE An increase in P21 expression as a consequence of downregulation of Snail accompanied by the induction of GADD45B expression is the main mechanism leading to cell cycle arrest in HCCs. 27134688 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 Biomarker disease BEFREE Induction of DNA damage-inducible gene GADD45beta contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cells. 21062976 2010
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 Biomarker disease BEFREE The growth-arrest DNA damage inducible gene 45beta (Gadd45beta) has been reported as a potential diagnostic marker for aggressive hepatocellular carcinoma. 18225533 2008
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 AlteredExpression disease BEFREE Down-regulation of GADD45beta, which is known to influence cell growth control, apoptosis, and cellular response to DNA damage, has been verified to be specific in hepatocellular carcinoma and consistent with the degree of malignancy. 17591973 2007
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 AlteredExpression disease BEFREE The overexpression of Gadd45beta in HCC cell lines also induces drug resistance against 5-FU. 17711513 2007
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 AlteredExpression disease BEFREE Down-regulation of GADD45beta has been verified to be specific in hepatocellular cancer (HCC) and consistent with the p53 mutant, and degree of malignancy of HCC. 15509538 2004
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 AlteredExpression disease LHGDN Moreover, we found that expression of GADD45beta was inversely correlated to the presence of mutant p53 in HCC tissue (P < 0.05). 12759252 2003
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 AlteredExpression disease BEFREE Moreover, we found that expression of GADD45beta was inversely correlated to the presence of mutant p53 in HCC tissue (P < 0.05). 12759252 2003
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE Among the nine genes, we focused on growth arrest and DNA-damage-inducible beta (GADD45B) and phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) as representative TFAP2C-regulated tumor suppressor genes. 31296259 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 AlteredExpression group BEFREE Matrine promoted the expression of GADD45B, a tumor suppressive gene that is involved in the regulation of cell cycle, DNA damage repair, cell survival, aging, apoptosis and other cellular processes through p38/JNK, ROS-GADD45B-p38, or other signal pathways. 29356020 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE The 19p13.3-GADD45B encoded protein product is involved in apoptosis and inhibiting tumor growth. 28870783 2017