IL20, interleukin 20, 50604

N. diseases: 111; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases
0.010 Biomarker group BEFREE The mucin gene, MUC5AC, is highly expressed both in chronic respiratory inflammatory diseases and inflammatory bowel disease where mucin secretion is regulated by members of the interleukin IL-20 subfamily. 31379870 2019
CUI: C0149870
Disease: De Quervain Disease
De Quervain Disease
0.010 Biomarker disease BEFREE Correlation Between IL-20 and De Quervain's Disease Severity. 30540601 2019
CUI: C0151936
Disease: Disorder of tendon
Disorder of tendon
0.010 Biomarker group BEFREE The main purpose of our study was to investigate the correlation between IL-20 and tumor necrosis factor (TNF-α) and clarify the potential predictor of tendinopathy progression. 30540601 2019
CUI: C0595921
Disease: Intraocular pressure disorder
Intraocular pressure disorder
0.010 Biomarker disease BEFREE Additionally, we determined the effects of IL-20 family cytokines on outflow rates in anterior segment perfusion culture, an in vitro model of intraocular pressure (IOP) regulation. 31205408 2019
CUI: C1568272
Disease: Tendinopathy
Tendinopathy
0.010 Biomarker disease BEFREE The main purpose of our study was to investigate the correlation between IL-20 and tumor necrosis factor (TNF-α) and clarify the potential predictor of tendinopathy progression. 30540601 2019
CUI: C0003872
Disease: Arthritis, Psoriatic
Arthritis, Psoriatic
0.010 Biomarker disease BEFREE This review describes the IL-20 family of cytokines in rheumatoid arthritis (RA) and spondyloartrhitits (SpA) including psoriatic arthritis. 30319661 2018
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome
0.010 AlteredExpression disease BEFREE No statistically significant difference was detected between the IL-20 levels of the control group and the inactive BD patient group (p = 0.2). 30048054 2018
CUI: C0021831
Disease: Intestinal Diseases
Intestinal Diseases
0.010 Biomarker group BEFREE The Interleukin-20 Cytokines in Intestinal Diseases. 29967613 2018
CUI: C0023895
Disease: Liver diseases
Liver diseases
0.010 Biomarker group BEFREE In this review, we focus on exploring the role of the IL-20 subfamily of cytokines in viral hepatitis, ALD, non-alcoholic steatohepatitis, and hepatocellular carcinoma, as well as delineating the main strategies explored so far in terms of therapeutic possibilities of the IL-20 subfamily of cytokines in liver disease. 29892294 2018
CUI: C0032269
Disease: Pneumococcal Infections
Pneumococcal Infections
0.010 Biomarker group BEFREE In the current study, our aim was to demonstrate the implication of IL-20 cytokines and their receptors and their role during experimental pneumococcal infection. 30361066 2018
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.010 Biomarker disease BEFREE Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae. 30361066 2018
CUI: C0035078
Disease: Kidney Failure
Kidney Failure
0.010 Biomarker disease BEFREE IL-20 is emerging as a potent angiogenic, chemotactic, and proinflammatory cytokine related to several chronic inflammatory disorders likes psoriasis, atherosclerosis, and renal failure. 29999545 2018
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.010 Biomarker disease BEFREE This suggests that the IL-20 subfamily of cytokines, similar to IL-10 might play a potentially crucial role in the modulation of T cell responses in active TB disease. 29684756 2018
CUI: C0042721
Disease: Viral hepatitis
Viral hepatitis
0.010 Biomarker group BEFREE In this review, we focus on exploring the role of the IL-20 subfamily of cytokines in viral hepatitis, ALD, non-alcoholic steatohepatitis, and hepatocellular carcinoma, as well as delineating the main strategies explored so far in terms of therapeutic possibilities of the IL-20 subfamily of cytokines in liver disease. 29892294 2018
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.010 Biomarker phenotype BEFREE In addition, anti-IL-20 mAb may attenuate the effect of IL-20 and suppress liver tumorigenesis <i>in vitro</i> and <i>in vivo</i>, indicating that anti-IL-20 mAbs may potentially serve as effective therapeutic agents for HCC. 30333881 2018
CUI: C0746025
Disease: Lumbar spondylolisthesis
Lumbar spondylolisthesis
0.010 Biomarker phenotype BEFREE The roles of IL-19 and IL-20 in the inflammation of degenerative lumbar spondylolisthesis. 30250404 2018
CUI: C0876973
Disease: Infectious Lung Disorder
Infectious Lung Disorder
0.010 Biomarker group BEFREE Collectively, this study highlights the implication of IL-20 related cytokines during lung infection by S. pneumoniae and might have therapeutic applications in bacterial pneumonia. 30361066 2018
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases
0.010 Biomarker group BEFREE The role of IL-20 in chronic kidney disease and diabetic nephropathy: Pathogenic and therapeutic implications. 29999545 2018
CUI: C3714636
Disease: Pneumonitis
Pneumonitis
0.010 Biomarker disease BEFREE Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae. 30361066 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.010 Biomarker group BEFREE Our results expand upon the current understanding of the regulatory mechanism of IL-20 in cancer. 28514748 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 AlteredExpression group BEFREE HCC tumor tissue expressed higher levels of IL-20 than did non-tumor tissue. 29242565 2017
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.010 AlteredExpression disease BEFREE RTQ-PCR and western blotting were used to determine IL-20-regulated OA-associated gene expression in OASFs and OACCs. 28426699 2017
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.010 Biomarker phenotype BEFREE The findings of this study suggest that IL-20 plays a role in the tumor progression of HCC. 29242565 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker group BEFREE Our results expand upon the current understanding of the regulatory mechanism of IL-20 in cancer. 28514748 2017
CUI: C1456868
Disease: Diabetic foot ulcer
Diabetic foot ulcer
0.010 Biomarker disease BEFREE Taken together, our data suggest that IL-20 subfamily cytokines, particularly IL-20, IL-22, and IL-24, might provide therapeutic benefit for patients with DFU. 28125663 2017