Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CLCN7 P51798 chloride voltage-gated channel 7 Ion channel 0.27 0.590 0.731 1
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846 4
OPRD1 P41143 opioid receptor delta 1 G-protein coupled receptor 3.3E-03 0.604 0.731 5
TACR3 P29371 tachykinin receptor 3 G-protein coupled receptor 1.8E-17 0.553 0.769 5
CCL22 O00626 C-C motif chemokine ligand 22 Signaling 8.4E-03 0.500 0.846 6
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846 6
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692 6
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423 6
CCR2 P41597 C-C motif chemokine receptor 2 2.3E-02 0.418 0.846 7
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 7
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 7
PPP1R9A Q9ULJ8 protein phosphatase 1 regulatory subunit 9A 1.1E-05 0.769 0.269 7
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885 8
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 8
PRKG1 Q13976 protein kinase cGMP-dependent 1 Kinase 1.00 0.603 0.769 8
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 9
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923 9
CCKBR P32239 cholecystokinin B receptor G-protein coupled receptor 2.1E-06 0.573 0.615 10
TJP1 Q07157 tight junction protein 1 Cell-cell junction 1.00 0.576 0.692 11
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885 14
TACR1 P25103 tachykinin receptor 1 G-protein coupled receptor 3.8E-04 0.502 0.885 15
BDKRB1 P46663 bradykinin receptor B1 G-protein coupled receptor 4.7E-03 0.619 0.731 16
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885 18