Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885 14
BDKRB1 P46663 bradykinin receptor B1 G-protein coupled receptor 4.7E-03 0.619 0.731 16
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885 8
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846 4
CCKBR P32239 cholecystokinin B receptor G-protein coupled receptor 2.1E-06 0.573 0.615 10
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
CCL22 O00626 C-C motif chemokine ligand 22 Signaling 8.4E-03 0.500 0.846 6
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
CCR2 P41597 C-C motif chemokine receptor 2 2.3E-02 0.418 0.846 7
CLCN7 P51798 chloride voltage-gated channel 7 Ion channel 0.27 0.590 0.731 1
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 19
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846 6
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 7
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 26
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 9
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 8
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692 6
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 54
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 40
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 24
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846 23