Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 69
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 54
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 40
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 40
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 25
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 23
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 9
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923 9
PPP1R9A Q9ULJ8 protein phosphatase 1 regulatory subunit 9A 1.1E-05 0.769 0.269 7
CCR2 P41597 C-C motif chemokine receptor 2 2.3E-02 0.418 0.846 7
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846 4
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
TJP1 Q07157 tight junction protein 1 Cell-cell junction 1.00 0.576 0.692 11
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885 18
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885 14
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885 8
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 7
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 26
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 19
BDKRB1 P46663 bradykinin receptor B1 G-protein coupled receptor 4.7E-03 0.619 0.731 16
TACR1 P25103 tachykinin receptor 1 G-protein coupled receptor 3.8E-04 0.502 0.885 15
CCKBR P32239 cholecystokinin B receptor G-protein coupled receptor 2.1E-06 0.573 0.615 10