|
rs6265
|
|
|
0.070 |
GeneticVariation |
BEFREE |
There was no evidence for an allelic or genotypic association of two polymorphisms (-1360C>T and 196G>A) of the BDNF gene with BPD.
|
12524161 |
2003 |
|
rs759834365
|
|
|
0.070 |
GeneticVariation |
BEFREE |
There was no evidence for an allelic or genotypic association of two polymorphisms (-1360C>T and 196G>A) of the BDNF gene with BPD.
|
12524161 |
2003 |
|
rs746682028
|
|
|
0.020 |
GeneticVariation |
BEFREE |
There was no evidence for an allelic or genotypic association of two polymorphisms (-1360C>T and 196G>A) of the BDNF gene with BPD.
|
12524161 |
2003 |
|
rs175174
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined three SNPs of the ZDHHC8 gene, including rs175174, by case-control association in Japanese patients with BPD (N=172) and controls (N=298) or patients with schizophrenia (N=407) and controls (N=497).
|
16150541 |
2005 |
|
rs6265
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Two family-based association studies showed that the Val allele of the functional polymorphism Val66Met in the BDNF gene is associated with BPD; however, others could not confirm the results.
|
16152572 |
2005 |
|
rs759834365
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Two family-based association studies showed that the Val allele of the functional polymorphism Val66Met in the BDNF gene is associated with BPD; however, others could not confirm the results.
|
16152572 |
2005 |
|
rs1311223100
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs1390938
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs1497020
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs2270637
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs2270641
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs2279709
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs3735835
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs988713
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs1457319153
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only one significant association was found with BPD positive infants: the N494H homozygous genotype (p=0.033).
|
17196572 |
2007 |
|
rs165599
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These data suggest that COMT genetic variation at SNP rs165599 is associated with BPD I and influences prefrontal aspects of verbal memory in bipolar patients and healthy controls.
|
17547583 |
2007 |
|
rs5030737
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In contrast, the heterozygous R52C mutation was associated with unfavorable outcome, including higher bronchopulmonary dysplasia prevalence.
|
17653692 |
2007 |
|
rs2229569
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Indeed, carrier states of genetic variants of cytokines (IFNgamma T+874A), adhesion molecules (L-selectin-Pro213Ser), elements of renin-angiotensin system (ACE-I/D), antioxidant enzymes (GST-P1 Val105Ile), and surfactant proteins (SPA1, SPB intron 4) has been identified as risk factors to BPD.
|
17726703 |
2007 |
|
rs371131106
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Indeed, carrier states of genetic variants of cytokines (IFNgamma T+874A), adhesion molecules (L-selectin-Pro213Ser), elements of renin-angiotensin system (ACE-I/D), antioxidant enzymes (GST-P1 Val105Ile), and surfactant proteins (SPA1, SPB intron 4) has been identified as risk factors to BPD.
|
17726703 |
2007 |
|
rs1800450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association was found between two SNPs and the development of bronchopulmonary dysplasia (BPD), defined as persistent oxygen requirement at 36 weeks postmenstrual age, adjusting for covariates GA, grade of respiratory distress syndrome and days on mechanical ventilation (rs1800450 (exon 1 at codon 54, B variant): odds ratio dominant model (OR)=3.59, 95% confidence interval (CI)=1.62-7.98; rs7096206 (-221, X variant): OR=2.40, 95% CI=1.16-4.96).
|
17898783 |
2007 |
|
rs7096206
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association was found between two SNPs and the development of bronchopulmonary dysplasia (BPD), defined as persistent oxygen requirement at 36 weeks postmenstrual age, adjusting for covariates GA, grade of respiratory distress syndrome and days on mechanical ventilation (rs1800450 (exon 1 at codon 54, B variant): odds ratio dominant model (OR)=3.59, 95% confidence interval (CI)=1.62-7.98; rs7096206 (-221, X variant): OR=2.40, 95% CI=1.16-4.96).
|
17898783 |
2007 |
|
rs6265
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The study demonstrates that the BDNF C-270T and Val66Met polymorphisms are unlikely to contribute to the genetic predisposition to BPD as a whole.
|
18242852 |
2008 |
|
rs759834365
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The study demonstrates that the BDNF C-270T and Val66Met polymorphisms are unlikely to contribute to the genetic predisposition to BPD as a whole.
|
18242852 |
2008 |
|
rs1610037
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping of seven single nucleotide polymorphisms (rs1893154; rs2846811; rs8192595; rs2856966; rs928978; rs2231187; rs1610037) was performed in BPD patients (n=570) and healthy controls (n=710).
|
18349695 |
2008 |
|
rs2284017
|
|
|
0.010 |
GeneticVariation |
BEFREE |
None of the 12 genotyped single nucleotide polymorphisms were associated with BPD, but three of them were significantly associated with lithium response: one in both cohorts (rs2284017) and two (rs2284018, rs5750285) each in a different cohort.
|
18408563 |
2008 |