|
rs1010419
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Identification of SPOCK2 as a susceptibility gene for bronchopulmonary dysplasia.
|
21836138 |
2011 |
|
rs10152333
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Identification of SPOCK2 as a susceptibility gene for bronchopulmonary dysplasia.
|
21836138 |
2011 |
|
rs1042606
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In our BPD cohort, 32% (n = 61) had PH.Of the DUSP SNPs evaluated, DUSP1 SNP rs322351 was less common, and DUSP5 SNPs rs1042606 and rs3793892 were more common in cases than in controls.
|
31330530 |
2020 |
|
rs1049269
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Identification of SPOCK2 as a susceptibility gene for bronchopulmonary dysplasia.
|
21836138 |
2011 |
|
rs10994336
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found no association in the ANK3 markers, but the rs10994336 variant was nominally associated with non-psychotic BPD (P = 0.046).
|
21767209 |
2011 |
|
rs10994336
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Following stratification by ethnicity, variants of the ANK3 gene (rs1938516 and rs10994336) were found to be associated with BPD in Malays (P-value=0.001 and 0.006, respectively).
|
24914473 |
2014 |
|
rs11199993
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correcting the multiple tests by permutation, one SNP (rs11199993), and a haplotype including this SNP, was found to be significantly associated with BPD.
|
22404656 |
2012 |
|
rs11265269
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Finally, SNP rs11265269 was identified as a risk factor of BPD (OR 1.8, p = 5.3 × 10<sup>-5</sup>), independently of the robust antenatal risk factors.
|
28839172 |
2017 |
|
rs1128306
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Logistic regression modeling of BPD as a function of rs1128306 genotype, age and DNA methylation uncovered an independent effect of DNA methylation in white blood cells (odds ratio (OR)=1.08, P=0.0077) and the overall sample (OR=1.24, P=0.0011).
|
21647149 |
2012 |
|
rs1217691063
|
|
|
0.020 |
GeneticVariation |
BEFREE |
MTHFR C677T was significantly associated with all of the combined psychiatric disorders (SZ, BPD and UDD); random effects odds ratio (OR)=1.26 for TT versus CC genotype carriers; confidence interval (CI) 1.09-1.46); meta-regression did not suggest moderating effects of psychiatric diagnosis, sex, ethnic group or year of publication.
|
21185933 |
2011 |
|
rs1217691063
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Meta-analysis showed that MTHFR C677T was significantly associated with SZ, the highest OR was found for the recessive model (for TT vs. CT + CC: OR = 1.34, 95% CI: 1.18-1.53); a marginal association of MTHFR C677T with increased risk of BPD has also been found for the recessive model (OR = 1.26, 95% CI: 1.00-1.59).
|
24938371 |
2015 |
|
rs12290811
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One SNP, rs12290811, located in the ODZ4 gene reached statistical significance (p=1.7×10(-4), Allelic odds ratio=1.21), a value very near to those reported in previous GWAS of BPD patients.
|
25124521 |
2014 |
|
rs1245560
|
|
|
0.710 |
GeneticVariation |
GWASDB |
Fine mapping confirmed the association of rs1245560 with bronchopulmonary dysplasia in both white and African populations with adjusted odds ratios of 2.96 (95% confidence interval [CI], 1.37-6.40) and 4.87 (95% CI, 1.88-12.63), respectively.
|
21836138 |
2011 |
|
rs1245560
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Fine mapping confirmed the association of rs1245560 with bronchopulmonary dysplasia in both white and African populations with adjusted odds ratios of 2.96 (95% confidence interval [CI], 1.37-6.40) and 4.87 (95% CI, 1.88-12.63), respectively.
|
21836138 |
2011 |
|
rs1311223100
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs1344706
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Meta-analysis showed that rs1344706 and rs7597593 were both associated with major mood disorders as well as diagnosis of either BPD or MDD, although neither of the analyses achieved a genome-wide level of statistical significance.
|
27784192 |
2017 |
|
rs1386494
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Strong LD was found among rs1386494, rs2171363 and rs4760816, but no positive association with BPD was found for haplotypes.
|
25152196 |
2015 |
|
rs1390938
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs1440306
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
A genome-wide association study (GWAS) for bronchopulmonary dysplasia.
|
23897914 |
2013 |
|
rs1440306
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
A genome-wide association study (GWAS) for bronchopulmonary dysplasia.
|
23897914 |
2013 |
|
rs1457319153
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only one significant association was found with BPD positive infants: the N494H homozygous genotype (p=0.033).
|
17196572 |
2007 |
|
rs1497020
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020).
|
16936705 |
2006 |
|
rs1610037
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping of seven single nucleotide polymorphisms (rs1893154; rs2846811; rs8192595; rs2856966; rs928978; rs2231187; rs1610037) was performed in BPD patients (n=570) and healthy controls (n=710).
|
18349695 |
2008 |
|
rs165599
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These data suggest that COMT genetic variation at SNP rs165599 is associated with BPD I and influences prefrontal aspects of verbal memory in bipolar patients and healthy controls.
|
17547583 |
2007 |
|
rs1705236
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In our analysis setting, we were not able to replicate the association of rs1705236 with BPD, nor did we find an association with SCZ.
|
20052686 |
2010 |