Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 27
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 27
CASP12 Q6UXS9 caspase 12 (gene/pseudogene) 1.3E-04 0.638 0.808 23
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 23
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846 23
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 22
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885 22
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 22
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808 21
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 20
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 20
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808 20
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 Ion channel 0.91 0.513 0.654 20
SCD O00767 stearoyl-CoA desaturase 0.97 0.490 0.808 19
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885 19
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808 19
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 18
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 18
ACE2 Q9BYF1 angiotensin I converting enzyme 2 Enzyme 1.00 0.477 0.769 17
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 17
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923 17
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 17
ADRB1 P08588 adrenoceptor beta 1 G-protein coupled receptor 2.9E-06 0.555 0.769 16