Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ERCC5 P28715 ERCC excision repair 5, endonuclease 2.7E-13 0.499 0.731 4
XPA P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 7.9E-05 0.520 0.846 4
XPC Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 3.7E-11 0.504 0.808 4
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 3
GNA11 P29992 G protein subunit alpha 11 Enzyme modulator 0.89 0.563 0.731 3
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808 3
MAP2K2 P36507 mitogen-activated protein kinase kinase 2 Kinase 0.97 0.534 0.731 3
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962 3
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808 2
PAK1 Q13153 p21 (RAC1) activated kinase 1 Kinase 1.3E-03 0.494 0.808 2
PPP6C O00743 protein phosphatase 6 catalytic subunit 0.86 0.729 0.231 2
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 2
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 2