Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2621
Gene Symbol: GAS6
GAS6
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.210 Biomarker RGD In the present study, therefore, we examined in vivo roles of Gas6 and Axl in an experimental model of mesangial proliferative glomerulonephritis induced by the injection of anti-Thy1.1 antibody (Thy1 GN). 11290560

2001

Entrez Id: 5997
Gene Symbol: RGS2
RGS2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 SusceptibilityMutation RGD Impaired response of regulator of Gαq signaling-2 mRNA to angiotensin II and hypertensive renal injury in Dahl salt-sensitive rats. 26606876

2016

Entrez Id: 144100
Gene Symbol: PLEKHA7
PLEKHA7
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. 25136115

2014

Entrez Id: 55328
Gene Symbol: RNLS
RNLS
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Lisinopril protects against the adriamycin nephropathy and reverses the renalase reduction: potential role of renalase in adriamycin nephropathy. 24022426

2013

Entrez Id: 2702
Gene Symbol: GJA5
GJA5
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Cx40 was detected in mesangial cells in normal rat glomeruli; its expression was reduced on days 3 and 7 and recovered to normal on day 14 following GN induction. 22945766

2013

Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Production and degradation of extracellular matrix in reversible glomerular lesions in rat model of habu snake venom-induced glomerulonephritis. 23224597

2012

Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Alterations in chromatin are associated with increases in collagen III expression in aging nephropathy. 20610530

2011

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Glomerulosclerosis was assessed by renal biopsy 8 wk later, and rats were divided into four groups with equivalent glomerulosclerosis: no further treatment, ARB, AT2 receptor antagonist, or combination. 20042458

2010

Entrez Id: 3675
Gene Symbol: ITGA3
ITGA3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Podocyte foot process effacement in very early phase of passive Heymann nephritis is not a prerequisite for proteinuria. 19662603

2009

Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Podocyte foot process effacement in very early phase of passive Heymann nephritis is not a prerequisite for proteinuria. 19662603

2009

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Angiotensin II receptor blockade inhibits acute glomerular injuries with the alteration of receptor expression. 19139720

2009

Entrez Id: 5551
Gene Symbol: PRF1
PRF1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Anti-perforin antibody treatment ameliorates experimental crescentic glomerulonephritis in WKY rats. 17622272

2007

Entrez Id: 2200
Gene Symbol: FBN1
FBN1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD During the acute phase of experimental Thy1.1 nephritis, glomerular fibrillin-1 messenger ribonucleic acid expression and protein immunoreactivity were significantly induced as compared to controls. 16395273

2006

Entrez Id: 2200
Gene Symbol: FBN1
FBN1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD We hypothesized that LTBP-1 and fibrillin-1 are coexpressed in the glomerulus and upregulated during glomerulonephritis. 16282705

2006

Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Expression of allograft inflammatory factor-1 in kidneys: A novel molecular component of podocyte. 17035944

2006

Entrez Id: 4052
Gene Symbol: LTBP1
LTBP1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD We hypothesized that LTBP-1 and fibrillin-1 are coexpressed in the glomerulus and upregulated during glomerulonephritis. 16282705

2006

Entrez Id: 4086
Gene Symbol: SMAD1
SMAD1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD These data suggest that the activation of STAT3 and Smad1 participates in the developing process of glomerulosclerosis in experimental glomerulonephritis. 15591053

2005

Entrez Id: 241
Gene Symbol: ALOX5AP
ALOX5AP
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 ModifyingMutation RGD Increased 5-lipoxygenase activating protein in immune-mediated experimental nephritis. 14733414

2004

Entrez Id: 6376
Gene Symbol: CX3CL1
CX3CL1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD This study investigated the potential of MCs to synthesize CX3CL1/fractalkine, a CX3C chemokine, both in vitro and in acute anti-Thy1 glomerulonephritis in rats. 14605272

2003

Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Expression of CX3CL1/fractalkine by mesangial cells in vitro and in acute anti-Thy1 glomerulonephritis in rats. 14605272

2003

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD The role of the renin-angiotensin system in cholesterol and puromycin mediated renal injury. 12495295

2002

Entrez Id: 558
Gene Symbol: AXL
AXL
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Gas6 regulates mesangial cell proliferation through Axl in experimental glomerulonephritis. 11290560

2001

Entrez Id: 308
Gene Symbol: ANXA5
ANXA5
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Localization of annexin V in rat normal kidney and experimental glomerulonephritis. 11271515

2001

Entrez Id: 729
Gene Symbol: C6
C6
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD C5b-9 membrane attack complex mediates endothelial cell apoptosis in experimental glomerulonephritis. 10807586

2000

Entrez Id: 6916
Gene Symbol: TBXAS1
TBXAS1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Effect of thromboxane A2 inhibition and antagonism on prostaglandin and leukotriene synthesis in glomerular immune injury. 10560941

1999