Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Expression of CX3CL1/fractalkine by mesangial cells in vitro and in acute anti-Thy1 glomerulonephritis in rats. 14605272

2003

Entrez Id: 2200
Gene Symbol: FBN1
FBN1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD During the acute phase of experimental Thy1.1 nephritis, glomerular fibrillin-1 messenger ribonucleic acid expression and protein immunoreactivity were significantly induced as compared to controls. 16395273

2006

Entrez Id: 2200
Gene Symbol: FBN1
FBN1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD We hypothesized that LTBP-1 and fibrillin-1 are coexpressed in the glomerulus and upregulated during glomerulonephritis. 16282705

2006

Entrez Id: 2353
Gene Symbol: FOS
FOS
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.210 Biomarker RGD Retinoid receptor-specific agonists alleviate experimental glomerulonephritis. 11880336

2002

Entrez Id: 2621
Gene Symbol: GAS6
GAS6
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.210 Biomarker RGD In the present study, therefore, we examined in vivo roles of Gas6 and Axl in an experimental model of mesangial proliferative glomerulonephritis induced by the injection of anti-Thy1.1 antibody (Thy1 GN). 11290560

2001

Entrez Id: 2702
Gene Symbol: GJA5
GJA5
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Cx40 was detected in mesangial cells in normal rat glomeruli; its expression was reduced on days 3 and 7 and recovered to normal on day 14 following GN induction. 22945766

2013

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.550 Biomarker RGD Renoprotective effect of rosuvastatin in DOCA-salt hypertensive rats. 19948880

2010

Entrez Id: 3675
Gene Symbol: ITGA3
ITGA3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Podocyte foot process effacement in very early phase of passive Heymann nephritis is not a prerequisite for proteinuria. 19662603

2009

Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Podocyte foot process effacement in very early phase of passive Heymann nephritis is not a prerequisite for proteinuria. 19662603

2009

Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Fibrinogen mediates platelet-polymorphonuclear leukocyte cooperation during immune-complex glomerulonephritis in rats. 8083378

1994

Entrez Id: 4052
Gene Symbol: LTBP1
LTBP1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD We hypothesized that LTBP-1 and fibrillin-1 are coexpressed in the glomerulus and upregulated during glomerulonephritis. 16282705

2006

Entrez Id: 4056
Gene Symbol: LTC4S
LTC4S
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Renal leukotriene C4 synthase: characterization, partial purification and alterations in experimental glomerulonephritis. 7827126

1995

Entrez Id: 4312
Gene Symbol: MMP1
MMP1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.220 Biomarker RGD The protective effect of BHR on renal function in rats with GS is possibly by way of influencing expressions of TGF-beta1, TIMP-1 and MMP1 to regulate the state of extracellular matrix and lessen the matrix aggregation. 21275176

2010

Entrez Id: 4312
Gene Symbol: MMP1
MMP1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.220 Biomarker RGD NMDA receptor-mediated activation of NADPH oxidase and glomerulosclerosis in hyperhomocysteinemic rats. 20406136

2010

Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Production and degradation of extracellular matrix in reversible glomerular lesions in rat model of habu snake venom-induced glomerulonephritis. 23224597

2012

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.240 Biomarker RGD NMDA receptor-mediated activation of NADPH oxidase and glomerulosclerosis in hyperhomocysteinemic rats. 20406136

2010

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.240 Biomarker RGD Differential regulation of glomerular gelatinase B (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in obese Zucker rats. 9300240

1997

Entrez Id: 931
Gene Symbol: MS4A1
MS4A1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Characterization of the mononuclear cell infiltrate in the glomerulus of rats with glomerulonephritis. 7538648

1995

Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.220 Therapeutic RGD Rats with progressive mesangioproliferative glomerulonephritis were treated from day 3 to day 7 after disease induction with a high-affinity oligonucleotide aptamer antagonist against platelet-derived growth factor-B chain (PDGF-B). 11316849

2001

Entrez Id: 80310
Gene Symbol: PDGFD
PDGFD
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.210 Biomarker RGD Thus, podocyte-specific overexpression of PDGF-D caused mesangioproliferative disease, glomerulosclerosis, and crescentic glomerulonephritis. 21866094

2011

Entrez Id: 144100
Gene Symbol: PLEKHA7
PLEKHA7
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. 25136115

2014

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.500 Therapeutic RGD Peroxisome proliferator-activated receptor-gamma agonist troglitazone protects against nondiabetic glomerulosclerosis in rats. 11318962

2001

Entrez Id: 5551
Gene Symbol: PRF1
PRF1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Biomarker RGD Anti-perforin antibody treatment ameliorates experimental crescentic glomerulonephritis in WKY rats. 17622272

2007

Entrez Id: 5724
Gene Symbol: PTAFR
PTAFR
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 Therapeutic RGD Mechanisms of glomerular injury in experimental immune nephritis. II. Effect of a platelet activating factor receptor antagonist in an autologous nephritis model. 1668710

1991

Entrez Id: 5997
Gene Symbol: RGS2
RGS2
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.200 SusceptibilityMutation RGD Impaired response of regulator of Gαq signaling-2 mRNA to angiotensin II and hypertensive renal injury in Dahl salt-sensitive rats. 26606876

2016