|
rs13281615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In premenopausal women, two environmental factors (history of breastfeeding, and history of benign breast disease) and four genetic variants (TOX3-rs3803662, ESR1-rs2046210, 8q24-rs13281615, and SLC4A7-rs4973768) were considered to be risk predictors, whereas three environmental factors (body mass index, history of breastfeeding, and hyperlipidemia), serum levels of testosterone and 25-hydroxyvitamin D, and two genetic variants (TOX3-rs3803662 and ESR1-rs2046210) were identified as risk predictors.
|
29029469 |
2017 |
|
rs2046210
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In premenopausal women, two environmental factors (history of breastfeeding, and history of benign breast disease) and four genetic variants (TOX3-rs3803662, ESR1-rs2046210, 8q24-rs13281615, and SLC4A7-rs4973768) were considered to be risk predictors, whereas three environmental factors (body mass index, history of breastfeeding, and hyperlipidemia), serum levels of testosterone and 25-hydroxyvitamin D, and two genetic variants (TOX3-rs3803662 and ESR1-rs2046210) were identified as risk predictors.
|
29029469 |
2017 |
|
rs3803662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In premenopausal women, two environmental factors (history of breastfeeding, and history of benign breast disease) and four genetic variants (TOX3-rs3803662, ESR1-rs2046210, 8q24-rs13281615, and SLC4A7-rs4973768) were considered to be risk predictors, whereas three environmental factors (body mass index, history of breastfeeding, and hyperlipidemia), serum levels of testosterone and 25-hydroxyvitamin D, and two genetic variants (TOX3-rs3803662 and ESR1-rs2046210) were identified as risk predictors.
|
29029469 |
2017 |
|
rs4973768
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In premenopausal women, two environmental factors (history of breastfeeding, and history of benign breast disease) and four genetic variants (TOX3-rs3803662, ESR1-rs2046210, 8q24-rs13281615, and SLC4A7-rs4973768) were considered to be risk predictors, whereas three environmental factors (body mass index, history of breastfeeding, and hyperlipidemia), serum levels of testosterone and 25-hydroxyvitamin D, and two genetic variants (TOX3-rs3803662 and ESR1-rs2046210) were identified as risk predictors.
|
29029469 |
2017 |
|
rs676210
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The risk factors age (P=0.008), body mass index (P<0.0001), GA+GG genotype in rs676210 (P=0.009), and alcohol consumption (P=0.056) contributed strongly to HL development.
|
28902930 |
2017 |
|
rs679899
|
|
|
0.010 |
GeneticVariation |
BEFREE |
APOB polymorphisms were identified using mass spectrometry, and five single nucleotide polymorphisms (rs1042034, rs2163204, rs512535, rs676210, and rs679899) and serum lipids were further analyzed. rs1042034 and rs676210 were significantly associated with HL (P<0.05).
|
28902930 |
2017 |
|
rs8450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, rs8450-AA genotype was associated with overweight or obesity (n=1215, OR=1.56, P=0.02), new-onset hyperlipidemia (n=1007, OR=1.76, P=0.007), and lower high-density lipoprotein-cholesterol (n=1214, β=-0.08, P=0.001).
|
26644205 |
2017 |
|
rs1941404
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results show that a SNP (rs1941404) in <i>NNMT</i> is significantly associated with hyperlipidemia, and the influence of rs1941404 variation on the resting energy expenditure may be the possible mechanism for rs1941404 variation to induce hyperlipidemia.
|
27999813 |
2016 |
|
rs2071410
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MATERIAL AND METHODS The odds ratios (ORs) and their 95% confidence intervals (95% CIs) were evaluated to assess the association of rs2071410 with TIA risk, and logistic regression was used to estimate the effects of various risk factors (e.g., diabetes, hypertension, and hyperlipidemia) on TIA.
|
27760099 |
2016 |
|
rs2107595
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup and multifactor dimensionality reduction analyses (MDR) further found the gene-environment interactions among SNP rs2107595, body mass index, type 2 diabetes and hyperlipidemia in CAD risk and the severity of coronary atherosclerosis.
|
27494404 |
2016 |
|
rs694539
|
|
|
0.010 |
GeneticVariation |
BEFREE |
At present, more than 200 <i>NNMT</i> single nucleotide polymorphisms (SNPs) have been identified in the databases of the human genome projects; however, the association between rs694539 variation and hyperlipidemia has not been reported yet, and whether there are any SNPs in <i>NNMT</i> significantly associated with hyperlipidemia is still unclear.
|
27999813 |
2016 |
|
rs7744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, the novel interaction between TLR4 rs11536889 and MyD88 rs7744 was related with an increased risk of CAD, that could be strengthened by the presence of hyperglycemia or hyperlipidemia.
|
26959040 |
2016 |
|
rs974389711
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The various genotypes of the ApoA1 G75A SNP influence the efficacy of lipid regulation by pravastatin and policosanol in patients with hyperlipidemia.
|
27323196 |
2016 |
|
rs2066853
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotype frequencies of AhR rs2066853 differed significantly between CAD and control subjects, while smoking and hyperlipidemia markedly promoted CAD risk relative to the AhR polymorphism.
|
25620626 |
2015 |
|
rs2241883
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of L-FABP T94A and MTP I128T polymorphisms with hyperlipidemia in Chinese subjects.
|
25663234 |
2015 |
|
rs2854744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Elders with GG genotype of rs6214 and AC or CC genotypes of rs2854744 had a 3.18-fold (95% CI 1.02-9.89) risk of having low ASMI compared with those with the AA and AA genotype, after adjusting for age, gender, smoking, exercise, hyperlipidemia, and albumin level.
|
25548030 |
2015 |
|
rs3816873
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of L-FABP T94A and MTP I128T polymorphisms with hyperlipidemia in Chinese subjects.
|
25663234 |
2015 |
|
rs6214
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Elders with GG genotype of rs6214 and AC or CC genotypes of rs2854744 had a 3.18-fold (95% CI 1.02-9.89) risk of having low ASMI compared with those with the AA and AA genotype, after adjusting for age, gender, smoking, exercise, hyperlipidemia, and albumin level.
|
25548030 |
2015 |
|
rs11066280
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three gene variants, rs12229654, rs17249754, and rs11066280, were significantly associated with metabolic disorders such as hyperlipidemia and diabetes (P = 0.00071 to 0.0097, respectively).
|
24142389 |
2014 |
|
rs12229654
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three gene variants, rs12229654, rs17249754, and rs11066280, were significantly associated with metabolic disorders such as hyperlipidemia and diabetes (P = 0.00071 to 0.0097, respectively).
|
24142389 |
2014 |
|
rs1444332461
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate the distribution of statin therapy correlated gene polymorphism allele CYP2D6*10 (C188T) in Ningxia Hui nationality and to discuss the relationship between the gene polymorphism allele CYP2D6*10 (C188T) and the lipid-lowering efficacy of simvastatin and hyperlipidemia.
|
24156754 |
2014 |
|
rs17249754
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three gene variants, rs12229654, rs17249754, and rs11066280, were significantly associated with metabolic disorders such as hyperlipidemia and diabetes (P = 0.00071 to 0.0097, respectively).
|
24142389 |
2014 |
|
rs198388
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup analyses performed by hyperlipidemia (HLP) demonstrated 3 polymorphisms, rs632793 (OR = 0.31, 95% CI 0.1-0.93, P = 0.04), rs198388 (OR = 0.26, 95% CI 0.09-0.79, P = 0.02) and rs198389 (OR = 0.26, 95% CI 0.09-0.80, P = 0.02) were associated with the reduced risk of LVD.
|
25400811 |
2014 |
|
rs198389
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup analyses performed by hyperlipidemia (HLP) demonstrated 3 polymorphisms, rs632793 (OR = 0.31, 95% CI 0.1-0.93, P = 0.04), rs198388 (OR = 0.26, 95% CI 0.09-0.79, P = 0.02) and rs198389 (OR = 0.26, 95% CI 0.09-0.80, P = 0.02) were associated with the reduced risk of LVD.
|
25400811 |
2014 |
|
rs632793
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup analyses performed by hyperlipidemia (HLP) demonstrated 3 polymorphisms, rs632793 (OR = 0.31, 95% CI 0.1-0.93, P = 0.04), rs198388 (OR = 0.26, 95% CI 0.09-0.79, P = 0.02) and rs198389 (OR = 0.26, 95% CI 0.09-0.80, P = 0.02) were associated with the reduced risk of LVD.
|
25400811 |
2014 |