|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our findings support the association of BDNF single nucleotide polymorphism rs6265 and depression, suggesting that this polymorphism may increase susceptibility to major depression in Mexican-Americans.
|
17632285 |
2007 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Brain-derived neurotrophic factor (BDNF) polymorphisms G196A and C270T are not associated with response to electroconvulsive therapy in major depressive disorder.
|
17036259 |
2007 |
|
rs6313
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The serotonin 2A (5-HT2A) receptor gene has been implicated in the pathogenesis of suicidal behavior by a genetic association between the 5-HT2A C102T silent polymorphism and suicidality in patients with major depression.
|
17221840 |
2007 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Brain-derived neurotrophic factor (BDNF) polymorphisms G196A and C270T are not associated with response to electroconvulsive therapy in major depressive disorder.
|
17036259 |
2007 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To examine the effect of the BDNF Val66Met polymorphism on hippocampal and amygdala volumes in patients with major depression and in healthy control subjects.
|
17404118 |
2007 |
|
rs5443
|
|
|
0.060 |
GeneticVariation |
BEFREE |
These findings, taken together with other studies suggesting an influence of the C825T polymorphism in major depressive disorder, support the hypothesis of the involvement of G-proteins in mood regulation.
|
16897596 |
2007 |
|
rs5443
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Relationship between G-protein beta-3 subunit C825T polymorphism and mirtazapine responses in Korean patients with major depression.
|
17943025 |
2007 |
|
rs1045642
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Our results show that SERTPR-LL genotype might predispose significantly better paroxetine treatment response compared to SS genotype in MDD patients and that variants G2677T and C3435T are not associated with therapeutic response to paroxetine in patients with major depressive disorder.
|
17914325 |
2007 |
|
rs746682028
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Brain-derived neurotrophic factor (BDNF) polymorphisms G196A and C270T are not associated with response to electroconvulsive therapy in major depressive disorder.
|
17036259 |
2007 |
|
rs2032582
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results show that SERTPR-LL genotype might predispose significantly better paroxetine treatment response compared to SS genotype in MDD patients and that variants G2677T and C3435T are not associated with therapeutic response to paroxetine in patients with major depressive disorder.
|
17914325 |
2007 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the present study, 256 patients with major depression (DSM-IV) of Caucasian descent were genotyped for the functional COMT val158met polymorphism and characterized for clinical response to antidepressive pharmacological treatment as measured by intra-individual changes of Hamilton Depression (HAM-D-21) scores over 6 weeks.
|
17522626 |
2008 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study suggests that the combined effect of rs2242446 and rs5569 in the NET gene could modify the response to the negative life events in triggering MD.
|
18779921 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A functional polymorphism of the brain-derived neurotrophic factor, BDNF Val66Met, is associated with risk for major depression alongside impairments in memory and selective attention.
|
18721847 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A functional polymorphism of the brain-derived neurotrophic factor, BDNF Val66Met, is associated with risk for major depression alongside impairments in memory and selective attention.
|
18721847 |
2008 |
|
rs5443
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The result suggests that C825T variants of GNB3 cannot play a major role as a predictor of treatment response as well as intolerance to SSRIs in Japanese patients with major depression.
|
18325652 |
2008 |
|
rs1045642
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Our results indicated that MDR1 variants G2677T and C3435T are not associated with therapeutic response to paroxetine in patients with major depressive disorder.
|
18550244 |
2008 |
|
rs1049353
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Therefore, the impact of cannabinoid receptor 1 gene (CNR1) variants rs1049353 and rs12720071 on antidepressant treatment response was evaluated in 256 Caucasian patients with Major Depression.
|
18579347 |
2008 |
|
rs120074175
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This mutant is equivalent to a rare human variant (R441H) identified in few individuals with unipolar major depression.
|
18212115 |
2008 |
|
rs2032582
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results indicated that MDR1 variants G2677T and C3435T are not associated with therapeutic response to paroxetine in patients with major depressive disorder.
|
18550244 |
2008 |
|
rs2242446
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study suggests that the combined effect of rs2242446 and rs5569 in the NET gene could modify the response to the negative life events in triggering MD.
|
18779921 |
2008 |
|
rs40184
|
|
|
0.020 |
GeneticVariation |
BEFREE |
As hypothesized, one of the polymorphisms (rs40184) moderated the effect of perceived maternal rejection on the onset of major depressive disorder, as well as on suicidal ideation.
|
18181793 |
2008 |
|
rs1176744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A polymorphism encoding the variation Y129S in the 5-HT3B subunit exists in high frequency in the general population and has been shown to be inversely correlated to the incidence of major depression in women.
|
18184810 |
2008 |
|
rs12720071
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, the impact of cannabinoid receptor 1 gene (CNR1) variants rs1049353 and rs12720071 on antidepressant treatment response was evaluated in 256 Caucasian patients with Major Depression.
|
18579347 |
2008 |
|
rs3825882
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Case-control analysis of 13 common variants showed modest nominal association of MDD-RE with rs4887379, rs6496463, and rs3825882 (p = .008, .048, and .034), which were in partial LD with four of five associated SNPs from the family-based experiment.
|
18367154 |
2008 |
|
rs4887379
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Case-control analysis of 13 common variants showed modest nominal association of MDD-RE with rs4887379, rs6496463, and rs3825882 (p = .008, .048, and .034), which were in partial LD with four of five associated SNPs from the family-based experiment.
|
18367154 |
2008 |