|
rs1799945
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Prevalence and clinical implications of HFE gene mutations (C282Y and H63D) in patients with chronic hepatitis B and C in Taiwan.
|
15780041 |
2005 |
|
rs1800562
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Prevalence and clinical implications of HFE gene mutations (C282Y and H63D) in patients with chronic hepatitis B and C in Taiwan.
|
15780041 |
2005 |
|
rs231775
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To assess the three polymorphism regions within cytotoxic T-lymphocyte antigen 4 (CTLA-4) gene, a C/T base exchange in the promoter region -318 (CTLA-4 -318C/T), an A/G substitution in the exon 1 position 49 (CTLA-4 49A/G), a T/C substitution in 1172 (CTLA-4 -1172T/C) in patients with chronic hepatitis B.
|
16489681 |
2006 |
|
rs3106796
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The 'A' allele of rs3106796 was highly associated with the CH [odds ratio (OR) = 1.62, P = 0.01], CIR (OR = 1.67, P = 0.01), and HCC (OR = 1.59, P = 0.03).
|
19000145 |
2008 |
|
rs2617160
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single marker association analysis was conducted and the SNP rs2617160 with a TT genotype in NKG2D was associated significantly with an increased risk of chronic hepatitis B (P = 0.044; OR = 1.49; 95% CI = 1.01-2.19).
|
20648603 |
2010 |
|
rs3077
|
|
|
0.760 |
GeneticVariation |
BEFREE |
A genome-wide association study identified single nucleotide polymorphisms (SNPs) rs3077 and rs9277535 located in the 3' untranslated regions of human leukocyte antigen (HLA) class II genes HLA-DPA1 and HLA-DPB1, respectively, as the independent variants most strongly associated with chronic hepatitis B.
|
21346778 |
2011 |
|
rs3077
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Chronic hepatitis B susceptibility loci in HLA-DP region (rs3077 and rs9277535) identified by genome-wide scan in Japanese population were validated in Chinese population.
|
21408128 |
2011 |
|
rs9277535
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Chronic hepatitis B susceptibility loci in HLA-DP region (rs3077 and rs9277535) identified by genome-wide scan in Japanese population were validated in Chinese population.
|
21408128 |
2011 |
|
rs9277535
|
|
|
0.760 |
GeneticVariation |
BEFREE |
A genome-wide association study identified single nucleotide polymorphisms (SNPs) rs3077 and rs9277535 located in the 3' untranslated regions of human leukocyte antigen (HLA) class II genes HLA-DPA1 and HLA-DPB1, respectively, as the independent variants most strongly associated with chronic hepatitis B.
|
21346778 |
2011 |
|
rs11556218
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs11556218T/G TG and GG genotypes were associated with significantly decreased risk of chronic hepatitis B compared with the TT genotype (OR = 0.49 and OR = 0.29).
|
22019522 |
2011 |
|
rs3077
|
|
|
0.760 |
GeneticVariation |
BEFREE |
We also found that the HLA-DPA1 and HLA-DPB1 genes were significantly associated with protective effects against chronic hepatitis B (CHB) in Japanese, Korean and other Asian populations, including Chinese and Thai individuals (P(meta) = 4.40×10⁻¹⁹ for rs3077 and P(meta) = 1.28×10⁻¹⁵ for rs9277542).
|
22737229 |
2012 |
|
rs12979860
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Cases were 49 HIV(+) patients with chronic hepatitis B (HBsAg(+) for more than 6 months) who had been genotyped for the rs12979860 SNP (protective CC genotype).
|
22324878 |
2012 |
|
rs1042522
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Fifty-eight patients with chronic hepatitis B and 30 healthy individuals were genotyped in terms of the p53 gene codon 72 Arg72Pro polymorphism by PCR-RFLP.
|
22892830 |
2012 |
|
rs1131691014
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Fifty-eight patients with chronic hepatitis B and 30 healthy individuals were genotyped in terms of the p53 gene codon 72 Arg72Pro polymorphism by PCR-RFLP.
|
22892830 |
2012 |
|
rs878854066
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Fifty-eight patients with chronic hepatitis B and 30 healthy individuals were genotyped in terms of the p53 gene codon 72 Arg72Pro polymorphism by PCR-RFLP.
|
22892830 |
2012 |
|
rs12980275
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To evaluate the role of host IL28B (interleukin 28B; interferon lambda 3) single nucleotide polymorphisms (SNPs) in predicting hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) susceptibility, three SNPs in the IL28B gene (rs12979860C/T, rs8099917G/T and rs12980275G/A) were examined in 330 subjects (including 154 HBV-related HCC patients, 86 non-HCC patients with chronic hepatitis B (CHB), 43 HBV self-limited infections and 47 healthy controls).
|
22310928 |
2012 |
|
rs4845384
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study suggested that rs4845384 in ADAR1 associates with treatment-induced clearance of chronic hepatitis B.
|
22449829 |
2012 |
|
rs9277542
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also found that the HLA-DPA1 and HLA-DPB1 genes were significantly associated with protective effects against chronic hepatitis B (CHB) in Japanese, Korean and other Asian populations, including Chinese and Thai individuals (P(meta) = 4.40×10⁻¹⁹ for rs3077 and P(meta) = 1.28×10⁻¹⁵ for rs9277542).
|
22737229 |
2012 |
|
rs3077
|
|
|
0.760 |
GeneticVariation |
GWASCAT |
A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.
|
23760081 |
2013 |
|
rs2856718
|
|
|
0.730 |
GeneticVariation |
GWASCAT |
A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.
|
23760081 |
2013 |
|
rs7453920
|
|
|
0.720 |
GeneticVariation |
GWASCAT |
A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.
|
23760081 |
2013 |
|
rs12979860
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Chronic hepatitis B and IL28B rs12979860 polymorphism: preliminary study.
|
24057245 |
2013 |
|
rs738409
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B.
|
23564580 |
2013 |
|
rs1042522
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study investigated the influence of combined p53 Arg72Pro and MDM2 SNP309 on the risk of developing HCC in patients with chronic hepatitis B virus infection, and evaluated the significance of the two combined SNPs on patient prognosis.
|
23292895 |
2013 |
|
rs1131691014
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study investigated the influence of combined p53 Arg72Pro and MDM2 SNP309 on the risk of developing HCC in patients with chronic hepatitis B virus infection, and evaluated the significance of the two combined SNPs on patient prognosis.
|
23292895 |
2013 |