Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1010023
rs1010023
PNPLA3
0.010 GeneticVariation BEFREE <i>PNPLA3</i> rs1010023 Predisposes Chronic Hepatitis B to Hepatic Steatosis but Improves Insulin Resistance and Glucose Metabolism. 28695131

2017
dbSNP: rs1042522
rs1042522
TP53
0.020 GeneticVariation BEFREE Fifty-eight patients with chronic hepatitis B and 30 healthy individuals were genotyped in terms of the p53 gene codon 72 Arg72Pro polymorphism by PCR-RFLP. 22892830

2012
dbSNP: rs1042522
rs1042522
TP53
0.020 GeneticVariation BEFREE This study investigated the influence of combined p53 Arg72Pro and MDM2 SNP309 on the risk of developing HCC in patients with chronic hepatitis B virus infection, and evaluated the significance of the two combined SNPs on patient prognosis. 23292895

2013
dbSNP: rs1053004
rs1053004
STAT3
0.020 GeneticVariation BEFREE Evaluation of STAT3 rs1053004 single nucleotide polymorphism in patients with chronic hepatitis B and hepatocellular carcinoma. 29307341

2017
dbSNP: rs1053004
rs1053004
STAT3
0.020 GeneticVariation BEFREE Association of Single Nucleotide Polymorphism rs1053004 in Signal Transducer and Activator of Transcription 3 (STAT3) with Susceptibility to Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B. 26163643

2015
dbSNP: rs1053005
rs1053005
STAT3
0.010 GeneticVariation BEFREE Association of polymorphism rs1053005 in STAT3 with chronic hepatitis B virus infection in Han Chinese population. 29609539

2018
dbSNP: rs1054690270
rs1054690270
GPT ; LOC101928953
0.010 GeneticVariation BEFREE Association of the S267F variant on NTCP gene and treatment response to pegylated interferon in patients with chronic hepatitis B: a multicentre study. 28635613

2018
dbSNP: rs1131691014
rs1131691014
TP53
0.020 GeneticVariation BEFREE Fifty-eight patients with chronic hepatitis B and 30 healthy individuals were genotyped in terms of the p53 gene codon 72 Arg72Pro polymorphism by PCR-RFLP. 22892830

2012
dbSNP: rs1131691014
rs1131691014
TP53
0.020 GeneticVariation BEFREE This study investigated the influence of combined p53 Arg72Pro and MDM2 SNP309 on the risk of developing HCC in patients with chronic hepatitis B virus infection, and evaluated the significance of the two combined SNPs on patient prognosis. 23292895

2013
dbSNP: rs11465817
rs11465817
IL23R
0.010 GeneticVariation BEFREE Three polymorphisms in the IL‑23R gene (rs10889677, rs1884444 and rs11465817) were examined in 84 cases of chronic hepatitis B (HBV), 67 cases of HBV‑related liver cirrhosis, 89 cases of HBV‑related HCC and 94 healthy controls using the polymerase chain reaction (PCR)‑restriction fragment length polymorphism method and DNA sequencing. 23807368

2013
dbSNP: rs11556218
rs11556218
IL16
0.010 GeneticVariation BEFREE The rs11556218T/G TG and GG genotypes were associated with significantly decreased risk of chronic hepatitis B compared with the TT genotype (OR = 0.49 and OR = 0.29). 22019522

2011
dbSNP: rs117648444
rs117648444
IFNL4
0.010 GeneticVariation BEFREE IFNL4 rs368234815 and rs117648444 variants predict off-treatment HBsAg seroclearance in IFN-treated HBeAg-negative chronic hepatitis B patients. 28732143

2018
dbSNP: rs11977021
rs11977021 		0.010 GeneticVariation BEFREE In this study, we genotyped two potentially functional single nucleotide polymorphisms (SNPs) in the visfatin promoter region, -1535C>T (rs61330082) and -3187G>A (rs11977021), in 120 HBV-related chronic hepatitis B (CHB) patients, 140 HBV-related liver cirrhosis (HBV-LC) patients, 243 HBV-related hepatocellular carcinoma (HBV-HCC) patients, and 224 asymptomatic HBV carriers. 27792999

2016
dbSNP: rs12252
rs12252
IFITM3
0.010 GeneticVariation BEFREE To address this issue, we explore the relationship between the IFITM3-rs12252 genetic variants and the progression of HCC in this study.A total of 336 candidates were enrolled in the study, including 156 patients with HBV related HCC and 180 patients with chronic Hepatitis B infections or liver cirrhosis. 30633185

2019
dbSNP: rs12354
rs12354
LTBR
0.010 GeneticVariation BEFREE The genotype and allele frequencies of rs12354 and rs3759333 had no statistical differences between chronic hepatitis B and HBV-related HCC patients. 28575727

2017
dbSNP: rs12614
rs12614
CFB ; CYP21A2
T 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015
dbSNP: rs12979860
rs12979860
IFNL4
0.050 GeneticVariation BEFREE We aimed to investigate whether IFNL3 polymorphism (rs12979860) influences the long-term response of chronic hepatitis B (CHB) treatment to conventional IFN. 24118626

2014
dbSNP: rs12979860
rs12979860
IFNL4
0.050 GeneticVariation BEFREE Chronic hepatitis B and IL28B rs12979860 polymorphism: preliminary study. 24057245

2013
dbSNP: rs12979860
rs12979860
IFNL4
0.050 GeneticVariation BEFREE Cases were 49 HIV(+) patients with chronic hepatitis B (HBsAg(+) for more than 6 months) who had been genotyped for the rs12979860 SNP (protective CC genotype). 22324878

2012
dbSNP: rs12979860
rs12979860
IFNL4
0.050 GeneticVariation BEFREE IL28B genetic variations (rs12979860) were genotyped by pyrosequencing of DNA samples from 137 individuals with chronic HBV infection [50 inactive carriers (IC), 34 chronic hepatitis B (CHB), 27 cirrhosis, 26 hepatocellular carcinoma (HCC)], and 19 healthy controls. 25837166

2015
dbSNP: rs12979860
rs12979860
IFNL4
0.050 GeneticVariation BEFREE In this study, we aimed to evaluate the effect of two single nucleotide polymorphisms (SNPs) of interleukin 28B (IL28B) (rs12979860C/T and rs8099917G/T) on chronic hepatitis B virus (CHB) infection in Thai population. 25664396

2015
dbSNP: rs12980275
rs12980275 		0.010 GeneticVariation BEFREE To evaluate the role of host IL28B (interleukin 28B; interferon lambda 3) single nucleotide polymorphisms (SNPs) in predicting hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) susceptibility, three SNPs in the IL28B gene (rs12979860C/T, rs8099917G/T and rs12980275G/A) were examined in 330 subjects (including 154 HBV-related HCC patients, 86 non-HCC patients with chronic hepatitis B (CHB), 43 HBV self-limited infections and 47 healthy controls). 22310928

2012
dbSNP: rs13419896
rs13419896
EPAS1
0.010 GeneticVariation BEFREE The aim of this study is to determine whether HIF-2a rs13419896 and rs6715787 single-nucleotide polymorphisms (SNPs) are associated with susceptibility to chronic hepatitis B (CHB), liver cirrhosis (LC), or hepatocellular carcinoma (HCC). 27384772

2016
dbSNP: rs1353702185
rs1353702185
MDM2
0.010 GeneticVariation BEFREE This study investigated the influence of combined p53 Arg72Pro and MDM2 SNP309 on the risk of developing HCC in patients with chronic hepatitis B virus infection, and evaluated the significance of the two combined SNPs on patient prognosis. 23292895

2013
dbSNP: rs1419881
rs1419881
TCF19
G 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015