Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2856718
rs2856718
0.730 GeneticVariation BEFREE Two recent genome-wide studies showed that the single-nucleotide polymorphisms in the HLA-DQ region (rs2856718 and rs9275572) were associated with chronic hepatitis B virus infection and chronic hepatitis C virus-associated hepatocellular carcinoma in Japanese patients. 24750255

2014

dbSNP: rs2856718
rs2856718
0.730 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) in HLA-DP (rs9277535 and rs3077) and HLA-DQ (rs2856718 and rs7453920) have been repeatedly associated with chronic hepatitis B and spontaneous HBV clearance. 28882445

2017

dbSNP: rs2856718
rs2856718
C 0.730 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015

dbSNP: rs2856718
rs2856718
0.730 GeneticVariation GWASCAT A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081

2013

dbSNP: rs2856718
rs2856718
0.730 GeneticVariation BEFREE We aimed to determine impacts of HLA-DQ polymorphisms and their interactions with HBV mutations on the risks of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). rs2856718 (A>G) and rs9275319 (A>G) were genotyped in 1342 healthy controls, 327 HBV surface antigen (HBsAg) seroclearance subjects, 611 asymptomatic HBsAg carriers (ASCs), 1144 chronic hepatitis B (CHB) patients, 734 LC patients, and 1531 HCC patients using quantitative PCR. 25281206

2014

dbSNP: rs2853953
rs2853953
A 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015

dbSNP: rs3130542
rs3130542
A 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015

dbSNP: rs11977021
rs11977021
0.010 GeneticVariation BEFREE In this study, we genotyped two potentially functional single nucleotide polymorphisms (SNPs) in the visfatin promoter region, -1535C>T (rs61330082) and -3187G>A (rs11977021), in 120 HBV-related chronic hepatitis B (CHB) patients, 140 HBV-related liver cirrhosis (HBV-LC) patients, 243 HBV-related hepatocellular carcinoma (HBV-HCC) patients, and 224 asymptomatic HBV carriers. 27792999

2016

dbSNP: rs12980275
rs12980275
0.010 GeneticVariation BEFREE To evaluate the role of host IL28B (interleukin 28B; interferon lambda 3) single nucleotide polymorphisms (SNPs) in predicting hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) susceptibility, three SNPs in the IL28B gene (rs12979860C/T, rs8099917G/T and rs12980275G/A) were examined in 330 subjects (including 154 HBV-related HCC patients, 86 non-HCC patients with chronic hepatitis B (CHB), 43 HBV self-limited infections and 47 healthy controls). 22310928

2012

dbSNP: rs148314165
rs148314165
0.010 GeneticVariation BEFREE Association of the tandem polymorphisms (rs148314165, rs200820567) in TNFAIP3 with chronic hepatitis B virus infection in Chinese Han population. 28784141

2017

dbSNP: rs200820567
rs200820567
0.010 GeneticVariation BEFREE Association of the tandem polymorphisms (rs148314165, rs200820567) in TNFAIP3 with chronic hepatitis B virus infection in Chinese Han population. 28784141

2017

dbSNP: rs8099917
rs8099917
0.010 GeneticVariation BEFREE In this study, we aimed to evaluate the effect of two single nucleotide polymorphisms (SNPs) of interleukin 28B (IL28B) (rs12979860C/T and rs8099917G/T) on chronic hepatitis B virus (CHB) infection in Thai population. 25664396

2015

dbSNP: rs9275319
rs9275319
0.010 GeneticVariation BEFREE We aimed to determine impacts of HLA-DQ polymorphisms and their interactions with HBV mutations on the risks of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). rs2856718 (A>G) and rs9275319 (A>G) were genotyped in 1342 healthy controls, 327 HBV surface antigen (HBsAg) seroclearance subjects, 611 asymptomatic HBsAg carriers (ASCs), 1144 chronic hepatitis B (CHB) patients, 734 LC patients, and 1531 HCC patients using quantitative PCR. 25281206

2014

dbSNP: rs9275572
rs9275572
0.010 GeneticVariation BEFREE Two recent genome-wide studies showed that the single-nucleotide polymorphisms in the HLA-DQ region (rs2856718 and rs9275572) were associated with chronic hepatitis B virus infection and chronic hepatitis C virus-associated hepatocellular carcinoma in Japanese patients. 24750255

2014

dbSNP: rs4845384
rs4845384
0.010 GeneticVariation BEFREE Our study suggested that rs4845384 in ADAR1 associates with treatment-induced clearance of chronic hepatitis B. 22449829

2012

dbSNP: rs510432
rs510432
0.010 GeneticVariation BEFREE Autophagy-Related 5 Gene rs510432 Polymorphism Is Associated with Hepatocellular Carcinoma in Patients with Chronic Hepatitis B Virus Infection. 30907204

2019

dbSNP: rs76844316
rs76844316
0.010 GeneticVariation BEFREE Our findings suggest that the genetic variants of rs76844316 in BTLA influence the susceptibility to severe chronic hepatitis B and might play a protective role against the progression of chronic hepatitis B. 29558758

2018

dbSNP: rs1883832
rs1883832
T 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015

dbSNP: rs12614
rs12614
T 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015

dbSNP: rs35761398
rs35761398
0.010 GeneticVariation BEFREE The impact of the cannabinoid receptor 2 (CB2) rs35761398 polymorphism on chronic hepatitis B (CHB) was evaluated in 106 consecutive biopsy-proven CHB patients naive for antiviral therapy. 25749560

2015

dbSNP: rs78900671
rs78900671
C 0.700 GeneticVariation GWASCAT Genome-wide Association Study Identifies Genetic Variants Associated With Early and Sustained Response to (Pegylated) Interferon in Chronic Hepatitis B Patients: The GIANT-B Study. 30715261

2019

dbSNP: rs3106796
rs3106796
0.010 GeneticVariation BEFREE The 'A' allele of rs3106796 was highly associated with the CH [odds ratio (OR) = 1.62, P = 0.01], CIR (OR = 1.67, P = 0.01), and HCC (OR = 1.59, P = 0.03). 19000145

2008

dbSNP: rs2794521
rs2794521
CRP
0.010 GeneticVariation BEFREE The present study investigated the association of the rs2794521 polymorphism in the CRP gene in individuals with chronic hepatitis B and C, correlating it with markers of hepatic inflammation, fibrosis scores, viral load, and plasma protein levels. 30810658

2019

dbSNP: rs231775
rs231775
0.010 GeneticVariation BEFREE To assess the three polymorphism regions within cytotoxic T-lymphocyte antigen 4 (CTLA-4) gene, a C/T base exchange in the promoter region -318 (CTLA-4 -318C/T), an A/G substitution in the exon 1 position 49 (CTLA-4 49A/G), a T/C substitution in 1172 (CTLA-4 -1172T/C) in patients with chronic hepatitis B. 16489681

2006

dbSNP: rs652888
rs652888
G 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015