Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12252
rs12252
0.010 GeneticVariation BEFREE To address this issue, we explore the relationship between the IFITM3-rs12252 genetic variants and the progression of HCC in this study.A total of 336 candidates were enrolled in the study, including 156 patients with HBV related HCC and 180 patients with chronic Hepatitis B infections or liver cirrhosis. 30633185

2019

dbSNP: rs2132039
rs2132039
0.010 GeneticVariation BEFREE A univariate-multivariate analysis showed that viral etiology (chronic hepatitis B, C) and the UDP glucuronosyltransferase family 2 member B28 (UGT2B28) genomic variant rs2132039 were independently associated with the age at presentation of HCC (all adjusted P < 0.05). 31805979

2019

dbSNP: rs2794521
rs2794521
CRP
0.010 GeneticVariation BEFREE The present study investigated the association of the rs2794521 polymorphism in the CRP gene in individuals with chronic hepatitis B and C, correlating it with markers of hepatic inflammation, fibrosis scores, viral load, and plasma protein levels. 30810658

2019

dbSNP: rs510432
rs510432
0.010 GeneticVariation BEFREE Autophagy-Related 5 Gene rs510432 Polymorphism Is Associated with Hepatocellular Carcinoma in Patients with Chronic Hepatitis B Virus Infection. 30907204

2019

dbSNP: rs7712322
rs7712322
0.010 GeneticVariation BEFREE FCER1A (rs7549785) and possibly POLR3G (rs7712322) are shown to be associated with peginterferon alfa-2a response in adult patients with chronic hepatitis B. 30972912

2019

dbSNP: rs1053005
rs1053005
0.010 GeneticVariation BEFREE Association of polymorphism rs1053005 in STAT3 with chronic hepatitis B virus infection in Han Chinese population. 29609539

2018

dbSNP: rs1054690270
rs1054690270
0.010 GeneticVariation BEFREE Association of the S267F variant on NTCP gene and treatment response to pegylated interferon in patients with chronic hepatitis B: a multicentre study. 28635613

2018

dbSNP: rs117648444
rs117648444
0.010 GeneticVariation BEFREE IFNL4 rs368234815 and rs117648444 variants predict off-treatment HBsAg seroclearance in IFN-treated HBeAg-negative chronic hepatitis B patients. 28732143

2018

dbSNP: rs2280714
rs2280714
0.010 GeneticVariation BEFREE Four <i>IFR5</i> SNPs (rs13242262A/T, rs77416878C/T, rs10488630A/G, and rs2280714T/C) were genotyped in clinically classified HBV patients [chronic hepatitis B (CHB). 29375210

2018

dbSNP: rs76844316
rs76844316
0.010 GeneticVariation BEFREE Our findings suggest that the genetic variants of rs76844316 in BTLA influence the susceptibility to severe chronic hepatitis B and might play a protective role against the progression of chronic hepatitis B. 29558758

2018

dbSNP: rs1010023
rs1010023
0.010 GeneticVariation BEFREE <i>PNPLA3</i> rs1010023 Predisposes Chronic Hepatitis B to Hepatic Steatosis but Improves Insulin Resistance and Glucose Metabolism. 28695131

2017

dbSNP: rs12354
rs12354
0.010 GeneticVariation BEFREE The genotype and allele frequencies of rs12354 and rs3759333 had no statistical differences between chronic hepatitis B and HBV-related HCC patients. 28575727

2017

dbSNP: rs148314165
rs148314165
0.010 GeneticVariation BEFREE Association of the tandem polymorphisms (rs148314165, rs200820567) in TNFAIP3 with chronic hepatitis B virus infection in Chinese Han population. 28784141

2017

dbSNP: rs1799724
rs1799724
LTA ; TNF
0.010 GeneticVariation BEFREE To test this hypothesis, we investigated the role of TNF-α polymorphism [-863C/A (rs1800630), -308G/A (rs1800629), -376G/A (rs1800750), -857C/T (rs1799724) and +489G/A (rs1800610)] in the susceptibility to chronic hepatitis B (CHB) infection. 29054398

2017

dbSNP: rs1800610
rs1800610
TNF
0.010 GeneticVariation BEFREE To test this hypothesis, we investigated the role of TNF-α polymorphism [-863C/A (rs1800630), -308G/A (rs1800629), -376G/A (rs1800750), -857C/T (rs1799724) and +489G/A (rs1800610)] in the susceptibility to chronic hepatitis B (CHB) infection. 29054398

2017

dbSNP: rs1800629
rs1800629
TNF
0.010 GeneticVariation BEFREE To test this hypothesis, we investigated the role of TNF-α polymorphism [-863C/A (rs1800630), -308G/A (rs1800629), -376G/A (rs1800750), -857C/T (rs1799724) and +489G/A (rs1800610)] in the susceptibility to chronic hepatitis B (CHB) infection. 29054398

2017

dbSNP: rs1800630
rs1800630
0.010 GeneticVariation BEFREE To test this hypothesis, we investigated the role of TNF-α polymorphism [-863C/A (rs1800630), -308G/A (rs1800629), -376G/A (rs1800750), -857C/T (rs1799724) and +489G/A (rs1800610)] in the susceptibility to chronic hepatitis B (CHB) infection. 29054398

2017

dbSNP: rs1800750
rs1800750
TNF
0.010 GeneticVariation BEFREE To test this hypothesis, we investigated the role of TNF-α polymorphism [-863C/A (rs1800630), -308G/A (rs1800629), -376G/A (rs1800750), -857C/T (rs1799724) and +489G/A (rs1800610)] in the susceptibility to chronic hepatitis B (CHB) infection. 29054398

2017

dbSNP: rs200820567
rs200820567
0.010 GeneticVariation BEFREE Association of the tandem polymorphisms (rs148314165, rs200820567) in TNFAIP3 with chronic hepatitis B virus infection in Chinese Han population. 28784141

2017

dbSNP: rs2736098
rs2736098
0.010 GeneticVariation BEFREE Association Between the Telomerase rs2736098_TT Genotype and a Lower Risk of Chronic Hepatitis B and Cirrhosis in Chinese Males. 28300824

2017

dbSNP: rs3759333
rs3759333
0.010 GeneticVariation BEFREE The genotype and allele frequencies of rs12354 and rs3759333 had no statistical differences between chronic hepatitis B and HBV-related HCC patients. 28575727

2017

dbSNP: rs11977021
rs11977021
0.010 GeneticVariation BEFREE In this study, we genotyped two potentially functional single nucleotide polymorphisms (SNPs) in the visfatin promoter region, -1535C>T (rs61330082) and -3187G>A (rs11977021), in 120 HBV-related chronic hepatitis B (CHB) patients, 140 HBV-related liver cirrhosis (HBV-LC) patients, 243 HBV-related hepatocellular carcinoma (HBV-HCC) patients, and 224 asymptomatic HBV carriers. 27792999

2016

dbSNP: rs13419896
rs13419896
0.010 GeneticVariation BEFREE The aim of this study is to determine whether HIF-2a rs13419896 and rs6715787 single-nucleotide polymorphisms (SNPs) are associated with susceptibility to chronic hepatitis B (CHB), liver cirrhosis (LC), or hepatocellular carcinoma (HCC). 27384772

2016

dbSNP: rs1800872
rs1800872
0.010 GeneticVariation BEFREE We conducted a case-control study to assess the role of two IL10 gene polymorphisms (rs1800896 and rs1800872) in susceptibility to liver cirrhosis, and their association with chronic hepatitis B in a Chinese population. 26909998

2016

dbSNP: rs3775290
rs3775290
0.010 GeneticVariation BEFREE Investigation of 1377C/T polymorphism of the Toll-like receptor 3 among patients with chronic hepatitis B. 27314608

2016