ALDH2, aldehyde dehydrogenase 2 family member, 217

N. diseases: 287; N. variants: 18
Source: BEFREE ×
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 471 223 0.700 None 1.000 134 4 1991 2019
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 117 24 0.600 None 1.000 10 1 1994 2018
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		disease Digestive System Diseases; Neoplasms Neoplastic Process 1231 169 0.500 None 0.982 56 2 1996 2020
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		group Digestive System Diseases; Neoplasms Neoplastic Process 1148 160 0.500 None 0.981 53 2 1996 2020
CUI: C0236664
Disease: Alcohol-Related Disorders
Alcohol-Related Disorders 		group Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 5 0.430 None 1.000 3 1992 2015
CUI: C0016382
Disease: Flushing
Flushing 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 62 9 0.400 None 0.959 48 2 1993 2019
CUI: C0279626
Disease: Squamous cell carcinoma of esophagus
Squamous cell carcinoma of esophagus 		disease Digestive System Diseases; Neoplasms Neoplastic Process 2021 320 0.400 None 0.970 33 3 1996 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		disease Digestive System Diseases; Neoplasms Neoplastic Process 5011 1186 0.400 None 0.941 17 3 1999 2017
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 202 54 0.400 None 0.947 17 1994 2019
CUI: C0004096
Disease: Asthma
Asthma 		disease Respiratory Tract Diseases; Immune System Diseases Disease or Syndrome 1731 714 0.360 None 1.000 6 1994 2017
CUI: C0001969
Disease: Alcoholic Intoxication
Alcoholic Intoxication 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 24 4 0.340 None 1.000 4 1982 2017
CUI: C0393756
Disease: Hangover from alcohol
Hangover from alcohol 		phenotype Chemically-Induced Disorders; Mental Disorders Sign or Symptom 15 0.340 None 1.000 4 2000 2017
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 863 307 0.340 None 0.500 4 2010 2018
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus 		group Endocrine System Diseases Disease or Syndrome 225 35 0.320 None 1.000 2 2000 2013
CUI: C0400966
Disease: Non-alcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease 		disease Digestive System Diseases Disease or Syndrome 1016 189 0.320 None 1.000 2 1 2016 2019
CUI: C0025209
Disease: Melanosis
Melanosis 		disease Skin and Connective Tissue Diseases Disease or Syndrome 17 5 0.320 None 1.000 2 2005 2019
CUI: C3241937
Disease: Nonalcoholic Steatohepatitis
Nonalcoholic Steatohepatitis 		disease Digestive System Diseases Disease or Syndrome 401 15 0.310 None 1.000 1 2016 2018
CUI: C0349464
Disease: Wernicke-Korsakoff Syndrome
Wernicke-Korsakoff Syndrome 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 7 0.310 None 1.000 1 2000 2000
CUI: C0042373
Disease: Vascular Diseases
Vascular Diseases 		group Cardiovascular Diseases Disease or Syndrome 660 40 0.310 None 1.000 1 2004 2008
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		disease Cardiovascular Diseases Disease or Syndrome 585 103 0.230 None 1.000 3 2008 2018
CUI: C0018799
Disease: Heart Diseases
Heart Diseases 		group Cardiovascular Diseases Disease or Syndrome 476 44 0.220 None 1.000 2 2011 2019
CUI: C0243026
Disease: Sepsis
Sepsis 		disease Pathological Conditions, Signs and Symptoms; Infections Disease or Syndrome 1340 139 0.210 None 1.000 1 2007 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		disease Cardiovascular Diseases Disease or Syndrome 1432 769 0.200 None 1.000 18 3 2010 2020
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		group Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 1515 412 0.160 None 0.857 6 1 2011 2019
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		disease Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 1104 586 0.150 None 1.000 5 4 2016 2019