|
Histiocytoma, Angiomatoid Fibrous
|
0.400 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Somatic mutation
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Histiocytoma
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
|
Human immunodeficiency virus (HIV) II infection category B1
|
0.070 |
Biomarker
|
disease |
BEFREE |
Human immunodeficiency virus transactivator protein (Tat) stimulates chemotaxis, calcium mobilization, and activation of human polymorphonuclear leukocytes: implications for Tat-mediated pathogenesis.
|
11069235 |
2000 |
|
Infection by human herpesvirus 6
|
0.010 |
Biomarker
|
disease |
BEFREE |
HHV-6 infection in the presence of Tat resulted in significantly higher LTR activation than that observed by Tat or HHV-6 alone, indicating that HHV-6 and Tat interact synergically.
|
1657039 |
1991 |
|
Clear Cell Sarcoma of Soft Tissue
|
0.360 |
GeneticVariation
|
disease |
BEFREE |
Clear cell sarcoma (CCS) harbors a pathognomonic chromosomal translocation fusing the Ewing's sarcoma gene (EWS) to the CREB family transcription factor ATF1 and exhibits melanocytic features.
|
16766266 |
2006 |
|
Histiocytoma, Angiomatoid Fibrous
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Angiomatoid fibrous histiocytoma: pleomorphic variant associated with multiplication of EWSR1-CREB1 fusion gene.
|
22038502 |
2012 |
|
Mental Depression
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Depression and fatigue during chronic IFN-α administration were associated with alterations in the expression (OAS2) and transcriptional control (CREB/ATF) of genes linked to behavioral disorders including CFS and major depression, further supporting an immune contribution to these diseases.
|
22152193 |
2012 |
|
Depressive disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Depression and fatigue during chronic IFN-α administration were associated with alterations in the expression (OAS2) and transcriptional control (CREB/ATF) of genes linked to behavioral disorders including CFS and major depression, further supporting an immune contribution to these diseases.
|
22152193 |
2012 |
|
Mental Depression
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Depression and fatigue during chronic IFN-α administration were associated with alterations in the expression (OAS2) and transcriptional control (CREB/ATF) of genes linked to behavioral disorders including CFS and major depression, further supporting an immune contribution to these diseases.
|
22152193 |
2012 |
|
Depressive disorder
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Depression and fatigue during chronic IFN-α administration were associated with alterations in the expression (OAS2) and transcriptional control (CREB/ATF) of genes linked to behavioral disorders including CFS and major depression, further supporting an immune contribution to these diseases.
|
22152193 |
2012 |
|
Depressed mood
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Depression and fatigue during chronic IFN-α administration were associated with alterations in the expression (OAS2) and transcriptional control (CREB/ATF) of genes linked to behavioral disorders including CFS and major depression, further supporting an immune contribution to these diseases.
|
22152193 |
2012 |
|
Drug habituation
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Habituation training increased CaMKII and CREB activity but had no effect on CaMKIV and ERK1/2 activity in the CA1, while inhibition of CaMKII but not ERK1/2 impaired "internal model" retention.
|
28230177 |
2017 |
|
Hepatitis B
|
0.040 |
Biomarker
|
disease |
BEFREE |
Hepatitis B virus X protein promotes CREB-mediated activation of miR-3188 and Notch signaling in hepatocellular carcinoma.
|
28574502 |
2017 |
|
Hepatitis
|
0.020 |
Biomarker
|
group |
BEFREE |
Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer.
|
29799025 |
2018 |
|
Hepatitis A
|
0.020 |
Biomarker
|
disease |
BEFREE |
Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer.
|
29799025 |
2018 |
|
Histiocytoma, Angiomatoid Fibrous
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor that has been associated with EWSR1-CREB1 gene fusion.
|
29932283 |
2018 |
|
Histiocytoma, Angiomatoid Fibrous
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Angiomatoid fibrous histiocytoma (AFH) is a rarely metastasizing neoplasm that typically occurs in the deep dermis and subcutis of the extremities of young patients, characterized by a t(2;22) translocation involving EWSR1 and CREB1.
|
31652145 |
2019 |
|
Leukemia, Myelocytic, Acute
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
CREB levels are elevated in blast cells from patients with acute myeloid leukemia.
|
15837624 |
2005 |
|
Leukemia, Myelocytic, Acute
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
CREB overexpression is associated with poor initial outcome of clinical disease in AML patients.
|
16196046 |
2005 |
|
Myeloproliferative disease
|
0.010 |
Biomarker
|
group |
BEFREE |
CREB transgenic mice also develop myeloproliferative disease after 1 year.
|
16196046 |
2005 |
|
Adult Liver Carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer.
|
20423907 |
2010 |
|
Liver and Intrahepatic Biliary Tract Carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer.
|
20423907 |
2010 |
|
Malignant neoplasm of liver
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer.
|
20423907 |
2010 |
|
Mood Disorders
|
0.400 |
Biomarker
|
group |
BEFREE |
CREB1 has previously been implicated in mood disorders, suicide, and antidepressant response.
|
21807415 |
2011 |