TPH2, tryptophan hydroxylase 2, 121278

N. diseases: 137; N. variants: 37
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1386494
rs1386494 		0.790 0.120 12 71958763 intron variant T/C;G snv 0.82
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		Mental Disorders 0.020 1.000 2 2007 2008
dbSNP: rs1473473
rs1473473 		0.925 0.080 12 72010598 intron variant C/A;T snv 0.81
CUI: C0232600
Disease: Self-induced vomiting
Self-induced vomiting 		Pathological Conditions, Signs and Symptoms 0.020 1.000 2 2011 2013
dbSNP: rs1473473
rs1473473 		0.925 0.080 12 72010598 intron variant C/A;T snv 0.81
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		Mental Disorders 0.020 1.000 2 2011 2013
dbSNP: rs1473473
rs1473473 		0.925 0.080 12 72010598 intron variant C/A;T snv 0.81
CUI: C0013473
Disease: Eating Disorders
Eating Disorders 		Mental Disorders 0.020 1.000 2 2011 2013
dbSNP: rs10784941
rs10784941 		1.000 0.040 12 71942732 intron variant A/G snv 0.40
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2012 2012
dbSNP: rs10879357
rs10879357 		1.000 0.040 12 72020783 intron variant A/G snv 0.59
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		Mental Disorders 0.010 1.000 1 2011 2011
dbSNP: rs11178999
rs11178999 		12 71939790 intron variant G/A snv 0.27
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		Behavior and Behavior Mechanisms 0.010 1.000 1 2019 2019
dbSNP: rs11179000
rs11179000 		0.925 0.040 12 71944848 intron variant A/T snv 0.31
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		Mental Disorders 0.010 < 0.001 1 2006 2006
dbSNP: rs11179000
rs11179000 		0.925 0.040 12 71944848 intron variant A/T snv 0.31
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		Mental Disorders 0.010 1.000 1 2011 2011
dbSNP: rs11179027
rs11179027 		1.000 0.040 12 71983532 intron variant G/C snv 0.26
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		Mental Disorders 0.010 1.000 1 2013 2013
dbSNP: rs12229394
rs12229394 		0.925 0.080 12 71999134 intron variant G/A snv 0.29
CUI: C0344315
Disease: Depressed mood
Depressed mood 		Behavior and Behavior Mechanisms 0.010 1.000 1 2010 2010
dbSNP: rs12229394
rs12229394 		0.925 0.080 12 71999134 intron variant G/A snv 0.29
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.010 1.000 1 2010 2010
dbSNP: rs12229394
rs12229394 		0.925 0.080 12 71999134 intron variant G/A snv 0.29
CUI: C0011570
Disease: Mental Depression
Mental Depression 		Behavior and Behavior Mechanisms 0.010 1.000 1 2010 2010
dbSNP: rs1386482
rs1386482 		0.827 0.080 12 72018792 intron variant T/G snv 0.52
CUI: C1970943
Disease: MAJOR AFFECTIVE DISORDER 4
MAJOR AFFECTIVE DISORDER 4 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs1386482
rs1386482 		0.827 0.080 12 72018792 intron variant T/G snv 0.52
CUI: C1852197
Disease: MAJOR AFFECTIVE DISORDER 1
MAJOR AFFECTIVE DISORDER 1 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs1386482
rs1386482 		0.827 0.080 12 72018792 intron variant T/G snv 0.52
CUI: C1839839
Disease: MAJOR AFFECTIVE DISORDER 2
MAJOR AFFECTIVE DISORDER 2 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs1386482
rs1386482 		0.827 0.080 12 72018792 intron variant T/G snv 0.52
CUI: C1970945
Disease: MAJOR AFFECTIVE DISORDER 6
MAJOR AFFECTIVE DISORDER 6 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs1386482
rs1386482 		0.827 0.080 12 72018792 intron variant T/G snv 0.52
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs1386483
rs1386483 		0.790 0.080 12 72018714 intron variant T/C snv 0.53
CUI: C0564567
Disease: Impulsive character (finding)
Impulsive character (finding) 		0.010 1.000 1 2012 2012
dbSNP: rs1386483
rs1386483 		0.790 0.080 12 72018714 intron variant T/C snv 0.53
CUI: C1839839
Disease: MAJOR AFFECTIVE DISORDER 2
MAJOR AFFECTIVE DISORDER 2 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs1386483
rs1386483 		0.790 0.080 12 72018714 intron variant T/C snv 0.53
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		Mental Disorders 0.010 1.000 1 2007 2007
dbSNP: rs1386483
rs1386483 		0.790 0.080 12 72018714 intron variant T/C snv 0.53
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		Behavior and Behavior Mechanisms 0.010 1.000 1 2009 2009
dbSNP: rs1386483
rs1386483 		0.790 0.080 12 72018714 intron variant T/C snv 0.53
CUI: C1970943
Disease: MAJOR AFFECTIVE DISORDER 4
MAJOR AFFECTIVE DISORDER 4 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs1386483
rs1386483 		0.790 0.080 12 72018714 intron variant T/C snv 0.53
CUI: C1970945
Disease: MAJOR AFFECTIVE DISORDER 6
MAJOR AFFECTIVE DISORDER 6 		Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs1386483
rs1386483 		0.790 0.080 12 72018714 intron variant T/C snv 0.53
CUI: C3160718
Disease: PARKINSON DISEASE, LATE-ONSET
PARKINSON DISEASE, LATE-ONSET 		0.010 1.000 1 2007 2007