TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs3093661
rs3093661 		1.000 6 31575981 intron variant G/A snv 3.5E-02
CUI: C1836230
Disease: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO 		0.700 1.000 2 2009 2010
dbSNP: rs3093661
rs3093661 		1.000 6 31575981 intron variant G/A snv 3.5E-02
CUI: C1836231
Disease: HIV-1, RESISTANCE TO
HIV-1, RESISTANCE TO 		0.700 1.000 2 2009 2010
dbSNP: rs3093661
rs3093661 		1.000 6 31575981 intron variant G/A snv 3.5E-02
CUI: C1836232
Disease: ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO
ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO 		0.700 1.000 2 2009 2010
dbSNP: rs3093661
rs3093661 		1.000 6 31575981 intron variant G/A snv 3.5E-02
CUI: C1836233
Disease: AIDS, PROGRESSION TO
AIDS, PROGRESSION TO 		0.700 1.000 2 2009 2010
dbSNP: rs1232013698
rs1232013698 		6 31577208 missense variant G/T snv 4.1E-06
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2009 2009
dbSNP: rs1250915035
rs1250915035 		0.925 6 31576537 missense variant C/T snv 4.0E-06
CUI: C0374997
Disease: Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site 		0.010 1.000 1 2017 2017
dbSNP: rs1250915035
rs1250915035 		0.925 6 31576537 missense variant C/T snv 4.0E-06
CUI: C3826128
Disease: Infection in children
Infection in children 		0.010 1.000 1 2017 2017
dbSNP: rs3093664
rs3093664 		6 31576865 intron variant A/G snv 6.9E-02 7.7E-02
CUI: C0043144
Disease: Wheezing
Wheezing 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2016 2016
dbSNP: rs3093664
rs3093664 		6 31576865 intron variant A/G snv 6.9E-02 7.7E-02
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		0.700 1.000 1 2018 2018
dbSNP: rs3093668
rs3093668 		1.000 6 31578718 downstream gene variant G/C snv 3.5E-02
CUI: C1836231
Disease: HIV-1, RESISTANCE TO
HIV-1, RESISTANCE TO 		0.700 1.000 1 2009 2009
dbSNP: rs3093668
rs3093668 		1.000 6 31578718 downstream gene variant G/C snv 3.5E-02
CUI: C1836232
Disease: ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO
ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO 		0.700 1.000 1 2009 2009
dbSNP: rs3093668
rs3093668 		1.000 6 31578718 downstream gene variant G/C snv 3.5E-02
CUI: C1836230
Disease: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO 		0.700 1.000 1 2009 2009
dbSNP: rs3093668
rs3093668 		1.000 6 31578718 downstream gene variant G/C snv 3.5E-02
CUI: C1836233
Disease: AIDS, PROGRESSION TO
AIDS, PROGRESSION TO 		0.700 1.000 1 2009 2009
dbSNP: rs281865419
rs281865419 		6 31577157 missense variant C/T snv 8.1E-06 7.0E-06
CUI: C4016415
Disease: TNF RECEPTOR BINDING, ALTERED
TNF RECEPTOR BINDING, ALTERED 		0.700 0
dbSNP: rs1411364031
rs1411364031 		0.882 0.040 6 31577502 missense variant T/C snv 7.0E-06
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1411364031
rs1411364031 		0.882 0.040 6 31577502 missense variant T/C snv 7.0E-06
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1411364031
rs1411364031 		0.882 0.040 6 31577502 missense variant T/C snv 7.0E-06
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		Cardiovascular Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1454071630
rs1454071630 		1.000 0.040 6 31577259 missense variant G/A;T snv 8.1E-06
CUI: C0343055
Disease: Generalized pustular psoriasis
Generalized pustular psoriasis 		Skin and Connective Tissue Diseases 0.010 1.000 1 2012 2012
dbSNP: rs56036015
rs56036015 		1.000 0.040 6 31575287 upstream gene variant A/C;G snv 7.0E-06; 1.4E-05
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		Respiratory Tract Diseases 0.010 1.000 1 2015 2015
dbSNP: rs756182468
rs756182468 		1.000 0.040 6 31575902 missense variant G/A snv 7.1E-05 2.4E-04
CUI: C0023348
Disease: Leprosy, Lepromatous
Leprosy, Lepromatous 		Infections 0.010 1.000 1 2010 2010
dbSNP: rs982610810
rs982610810 		1.000 0.040 6 31575766 missense variant G/A snv 4.2E-06
CUI: C0033860
Disease: Psoriasis
Psoriasis 		Skin and Connective Tissue Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2008 2008