| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.900 | None | 0.981 | 2446 | 58 | 1987 | 2020 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.700 | None | 0.971 | 641 | 56 | 1990 | 2020 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.700 | None | 0.990 | 958 | 22 | 1988 | 2020 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.700 | None | 0.946 | 3007 | 20 | 1991 | 2020 | ||||||||
|
sortilin related receptor 1 | 0.582 | 0.692 | 7.7E-11 |
|
disease | 0.500 | None | 0.973 | 98 | 15 | 2004 | 2020 | ||||||||
|
triggering receptor expressed on myeloid cells 2 | 0.519 | 0.769 | 3.3E-09 |
|
disease | 0.700 | limited | 0.977 | 211 | 13 | 2007 | 2020 | ||||||||
|
presenilin 2 | 0.550 | 0.654 | 5.4E-04 |
|
disease | 0.500 | None | 0.977 | 166 | 12 | 1995 | 2020 | ||||||||
|
ATP binding cassette subfamily A member 1 | 0.467 | 0.846 | 1.5E-13 |
|
disease | 0.200 | None | 0.904 | 51 | 12 | 2003 | 2020 | ||||||||
|
choline O-acetyltransferase | 0.520 | 0.808 | 5.6E-11 |
|
disease | 0.300 | None | 0.981 | 50 | 11 | 1987 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.600 | None | 0.958 | 237 | 10 | 1991 | 2020 | ||||||||
|
cytochrome P450 family 19 subfamily A member 1 | 0.410 | 0.885 | 1.7E-05 |
|
disease | 0.100 | None | 1.000 | 21 | 10 | 2004 | 2019 | ||||||||
|
insulin degrading enzyme | 0.604 | 0.577 | 6.6E-03 |
|
disease | 0.600 | None | 0.955 | 83 | 9 | 2000 | 2019 | ||||||||
|
ATP binding cassette subfamily A member 7 | 0.644 | 0.577 | 2.1E-55 |
|
disease | 0.500 | None | 0.985 | 60 | 9 | 2011 | 2019 | ||||||||
|
leucine rich repeat kinase 2 | 0.510 | 0.808 | 2.6E-30 |
|
disease | 0.100 | None | 0.783 | 22 | 8 | 2005 | 2019 | ||||||||
|
estrogen receptor 2 | 0.400 | 0.923 | 4.5E-08 |
|
disease | 0.100 | None | 1.000 | 16 | 8 | 2001 | 2020 | ||||||||
|
BDNF antisense RNA | 0.638 | 0.538 |
|
disease | 0.010 | None | 1.000 | 1 | 8 | 2018 | 2018 | |||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.900 | strong | 0.915 | 85 | 7 | 1998 | 2020 | ||||||||
|
ADAM metallopeptidase domain 10 | 0.489 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.986 | 68 | 7 | 2000 | 2019 | ||||||||
|
granulin precursor | 0.435 | 0.846 | 7.0E-02 |
|
disease | 0.200 | None | 0.970 | 66 | 7 | 2006 | 2019 | ||||||||
|
low density lipoprotein receptor | 0.449 | 0.885 | 9.8E-24 |
|
disease | 0.100 | None | 0.929 | 42 | 7 | 1997 | 2019 | ||||||||
|
complement C3b/C4b receptor 1 (Knops blood group) | 0.533 | 0.808 | 1.6E-35 |
|
disease | 0.500 | None | 0.971 | 26 | 7 | 2009 | 2019 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 0.400 | None | 0.907 | 53 | 6 | 2000 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 0.927 | 40 | 6 | 1999 | 2020 | ||||||||
|
GRB2 associated binding protein 2 | 0.563 | 0.692 | 0.98 |
|
disease | 0.200 | None | 0.826 | 21 | 6 | 2007 | 2018 | ||||||||
|
vitamin D receptor | 0.352 | 0.885 | 1.7E-05 |
|
disease | 0.100 | None | 1.000 | 12 | 6 | 2007 | 2020 |