Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7574865
rs7574865
0.030 GeneticVariation BEFREE This study was aimed at investigating the role of rs7574865, a single nucleotide polymorphism (SNP) in STAT4, in patients with chronic hepatitis B (CHB) treated with pegylated interferon (PEG-IFN). 31421662

2019

dbSNP: rs7549785
rs7549785
0.710 GeneticVariation BEFREE FCER1A (rs7549785) and possibly POLR3G (rs7712322) are shown to be associated with peginterferon alfa-2a response in adult patients with chronic hepatitis B. 30972912

2019

dbSNP: rs7549785
rs7549785
0.710 GeneticVariation GWASCAT FCER1A (rs7549785) and possibly POLR3G (rs7712322) are shown to be associated with peginterferon alfa-2a response in adult patients with chronic hepatitis B. 30972912

2019

dbSNP: rs7453920
rs7453920
0.720 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) in HLA-DP (rs9277535 and rs3077) and HLA-DQ (rs2856718 and rs7453920) have been repeatedly associated with chronic hepatitis B and spontaneous HBV clearance. 28882445

2017

dbSNP: rs7453920
rs7453920
0.720 GeneticVariation BEFREE Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population. 28613373

2017

dbSNP: rs7453920
rs7453920
G 0.720 GeneticVariation GWASCAT A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese. 24940741

2014

dbSNP: rs7453920
rs7453920
0.720 GeneticVariation GWASCAT A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081

2013

dbSNP: rs7453920
rs7453920
A 0.720 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015

dbSNP: rs738409
rs738409
0.030 GeneticVariation BEFREE Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B. 23564580

2013

dbSNP: rs738409
rs738409
0.030 GeneticVariation BEFREE We aimed to assess the association between the patatin-like phospholipase domain-containing-3 (PNPLA3) I148M polymorphism, liver histology and long-term outcome in chronic hepatitis B (CHB) patients. 25284145

2015

dbSNP: rs738409
rs738409
0.030 GeneticVariation BEFREE The aim of the present study was to evaluate the influence of the PNPLA3 I148M polymorphisms on the clinical, histological, viral, and host parameters in Italian patients with chronic hepatitis B (CHB). 25986529

2015

dbSNP: rs7095891
rs7095891
0.010 GeneticVariation BEFREE Single nucleotide polymorphisms rs2120131, rs4935047, and rs7095891 in the MBL2 gene show no association with susceptibility to chronic hepatitis B in a Chinese Han population. 23417614

2013

dbSNP: rs705382
rs705382
0.010 GeneticVariation BEFREE The objective of this study was to explore the association of PON1 rs662 and rs705382 with the risk of chronic hepatitis B (CHB), hepatitis B virus-related liver cirrhosis (LC), and hepatocellular carcinoma (HCC) in patients living in the Guangxi region of southern China. 26632904

2015

dbSNP: rs6715787
rs6715787
0.010 GeneticVariation BEFREE The aim of this study is to determine whether HIF-2a rs13419896 and rs6715787 single-nucleotide polymorphisms (SNPs) are associated with susceptibility to chronic hepatitis B (CHB), liver cirrhosis (LC), or hepatocellular carcinoma (HCC). 27384772

2016

dbSNP: rs662
rs662
0.010 GeneticVariation BEFREE The objective of this study was to explore the association of PON1 rs662 and rs705382 with the risk of chronic hepatitis B (CHB), hepatitis B virus-related liver cirrhosis (LC), and hepatocellular carcinoma (HCC) in patients living in the Guangxi region of southern China. 26632904

2015

dbSNP: rs652888
rs652888
G 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015

dbSNP: rs641738
rs641738
0.020 GeneticVariation BEFREE We conclude that the variant MBOAT7 rs641738 genotype is not associated with spontaneous clearance of HBV and HCV infections or with the progression of liver disease in chronic hepatitis B or C in a genetic context of Mediterranean patients. 30116012

2018

dbSNP: rs641738
rs641738
0.020 GeneticVariation BEFREE The membrane-bound O-acyltransferase domain-containing 7 variant rs641738 increases inflammation and fibrosis in chronic hepatitis B. 28109005

2017

dbSNP: rs61886277
rs61886277
T 0.700 GeneticVariation GWASCAT Genome-wide Association Study Identifies Genetic Variants Associated With Early and Sustained Response to (Pegylated) Interferon in Chronic Hepatitis B Patients: The GIANT-B Study. 30715261

2019

dbSNP: rs61330082
rs61330082
0.010 GeneticVariation BEFREE In this study, we genotyped two potentially functional single nucleotide polymorphisms (SNPs) in the visfatin promoter region, -1535C>T (rs61330082) and -3187G>A (rs11977021), in 120 HBV-related chronic hepatitis B (CHB) patients, 140 HBV-related liver cirrhosis (HBV-LC) patients, 243 HBV-related hepatocellular carcinoma (HBV-HCC) patients, and 224 asymptomatic HBV carriers. 27792999

2016

dbSNP: rs58542926
rs58542926
0.010 GeneticVariation BEFREE The TM6SF2 E167K substitution promotes steatosis and lipid abnormalities in part by altering TM6SF2 and microsomal triglyceride transfer protein expression and differentially impacts CHC and chronic hepatitis B viral load, while effects on fibrosis are marginal.(Hepatology 2016;64:34-46). 26822232

2016

dbSNP: rs510432
rs510432
0.010 GeneticVariation BEFREE Autophagy-Related 5 Gene rs510432 Polymorphism Is Associated with Hepatocellular Carcinoma in Patients with Chronic Hepatitis B Virus Infection. 30907204

2019

dbSNP: rs4935047
rs4935047
0.010 GeneticVariation BEFREE Single nucleotide polymorphisms rs2120131, rs4935047, and rs7095891 in the MBL2 gene show no association with susceptibility to chronic hepatitis B in a Chinese Han population. 23417614

2013

dbSNP: rs4845384
rs4845384
0.010 GeneticVariation BEFREE Our study suggested that rs4845384 in ADAR1 associates with treatment-induced clearance of chronic hepatitis B. 22449829

2012

dbSNP: rs422951
rs422951
G 0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187

2015