Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR 		P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.900 strong 0.977 173 35 1982 2020
Entrez Id: 338
Gene Symbol: APOB
APOB 		P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.900 strong 0.985 66 5 1987 2019
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9 		Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.700 strong 0.966 119 12 2003 2020
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.700 None 0.957 94 4 1985 2019
Entrez Id: 1581
Gene Symbol: CYP7A1
CYP7A1 		P22680 cytochrome P450 family 7 subfamily A member 1 Enzyme 91 0.576 0.615 2.5E-04 0.700 None 1.000 12 1 1993 2020
Entrez Id: 4023
Gene Symbol: LPL
LPL 		P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.680 None 1.000 9 0 1993 2019
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR 		P04035 3-hydroxy-3-methylglutaryl-CoA reductase 154 0.529 0.692 1.00 0.600 None 1.000 20 1 1978 2019
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1 		O95477 ATP binding cassette subfamily A member 1 Transporter 291 0.467 0.846 1.5E-13 0.550 limited 1.000 6 0 2002 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP 		P41159 leptin 931 0.349 0.846 0.46 0.540 None 1.000 6 0 2012 2017
Entrez Id: 3990
Gene Symbol: LIPC
LIPC 		P11150 lipase C, hepatic type Enzyme 120 0.585 0.654 3.3E-07 0.540 None 1.000 5 0 1995 2019
Entrez Id: 1071
Gene Symbol: CETP
CETP 		P11597 cholesteryl ester transfer protein 188 0.512 0.731 1.2E-23 0.500 None 0.923 13 1 1995 2019
Entrez Id: 26119
Gene Symbol: LDLRAP1
LDLRAP1 		Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 64 0.641 0.538 6.5E-06 0.490 strong 1.000 10 1 2002 2013
Entrez Id: 64241
Gene Symbol: ABCG8
ABCG8 		Q9H221 ATP binding cassette subfamily G member 8 Transporter 116 0.573 0.538 2.4E-20 0.470 strong 1.000 8 2 2004 2018
Entrez Id: 345
Gene Symbol: APOC3
APOC3 		P02656 apolipoprotein C3 153 0.531 0.731 1.0E-02 0.460 None 1.000 6 0 2001 2019
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5 		Q9H222 ATP binding cassette subfamily G member 5 Transporter 108 0.592 0.577 3.1E-21 0.460 strong 1.000 6 2 2004 2019
Entrez Id: 3988
Gene Symbol: LIPA
LIPA 		P38571 lipase A, lysosomal acid type Enzyme 130 0.564 0.654 5.5E-07 0.440 strong 1.000 4 1 2013 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA 		P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.400 None 0.957 23 0 1994 2019
Entrez Id: 335
Gene Symbol: APOA1
APOA1 		P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.360 None 0.833 6 0 1990 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1 		P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.350 None 0.833 6 0 1999 2019
Entrez Id: 949
Gene Symbol: SCARB1
SCARB1 		Q8WTV0 scavenger receptor class B member 1 Receptor 116 0.559 0.731 6.6E-02 0.350 None 1.000 5 1 2003 2019
Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1 		P19320 vascular cell adhesion molecule 1 406 0.422 0.808 0.80 0.340 None 1.000 5 0 1993 2017
Entrez Id: 6401
Gene Symbol: SELE
SELE 		P16581 selectin E 327 0.447 0.808 7.9E-10 0.320 None 1.000 3 0 2003 2008
Entrez Id: 1066
Gene Symbol: CES1
CES1 		P23141 carboxylesterase 1 Enzyme 80 0.590 0.692 3.3E-15 0.310 None 1.000 2 0 2003 2018
Entrez Id: 8013
Gene Symbol: NR4A3
NR4A3 		Q92570 nuclear receptor subfamily 4 group A member 3 Nuclear receptor 186 0.502 0.808 0.91 0.310 None 1.000 2 0 2005 2010
Entrez Id: 26228
Gene Symbol: STAP1
STAP1 		Q9ULZ2 signal transducing adaptor family member 1 Receptor 8 0.792 0.231 1.7E-05 0.310 limited 1.000 2 0 2014 2018